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DU PA Occ/int Lu Dis
Duke PA Occupational/Interstitial/GranulomatousLung Disease
Question | Answer |
---|---|
a virtual space between individual alveoli | interstitium |
from inhalation of silica | silicosis |
The chest film will reveal diffuse rounded opacities, Contraction of the lungs may occur, Upper lung zones are primarily affected | coal miner's lung |
black lung | coal miner's lung |
occupational lung disease caused by the inhalation of dust | pneumoconiosis |
Most commonly associated with mining, insulation, shipbuilding, cement mixing and sandblasting related occupations | silicosis |
Higher rate of pulmonary tuberculosis in ____ patients | silicosis |
Hilar lymph nodes calcify forming “eggshell” calcifications on chest films | silicosis |
may lead to pleural disease characterized by plaques, effusion and fibrosis | asbestosis |
Mesothelioma, Bronchogenic Carcinoma are malignancies caused by | asbestosis |
“Pleural Plaques” are seen on chest films | asbestosis |
diagnosis is based largely on the history of exposure and latency period. 20-30 year exposure history | asbestosis |
Allergic pulmonary condition caused by inhalation of organic materials | Hypersensitivity Pneumonitis |
Known causative agents include bacteria, molds, human and animal proteins and resins | Hypersensitivity Pneumonitis |
Abrupt onset of fever, cough & dyspnea within 4-8 hours of exposureInfiltrates in the mid-to-lower lung distributionResolution within 24 hours, after removal from exposureOften mistaken for community-acquired pneumonia, treated with antibiotics | Hypersensitivity Pneumonitis |
Characterized as lung injury caused by the inhalation of nitrogen dioxide gas | Silo-Filler’s Disease |
Approximately ___ of patients admitted to the burn unit have pulmonary injury due to smoke inhalation | 1/3 |
Carbon monoxide and cyanide poisoning impairs oxygenation causing tissue hypoxia | smoke inhalation |
Ensuing airway edema and mucosal sloughing occurs | smoke inhalation |
Routine use of corticosteroids and antibiotics has not been proven to be effective in treatment of | smoke inhalation |
Topical administration of epinephrine may be used to reduce airway edema | smoke inhalation |
The death rate among patients experiencing severe burn and inhalational injuries can be >__ | 50% |
_____ cannot differentiate carboxyhemoglobin from oxyhemoglobin. | pulse oximetry |
CO has a ____ higher affinity for hemoglobin than does oxygen | 250 X |
____ deposits in the alveoli and the interstitium results in irriversible fibrosis | Fibrin |
Loss of functional alveolar-capillary units,Impaired gas exchange that leads to hypoxemia and hypercapnia, Impaired lung compliance (stiff lungs)Progresses into Restrictive Lung Disease: smaller lung volumes and capacities (TLC, Tidal Volumes) | interstitial lung disease |
Patchy “Ground Glass” appearance, Reticular (network) pattern, Honeycombing (thick-walled cystic spaces) in the lung periphery | interstitial lung disease |
A nodular inflammatory lesion that may contain epithelial cells, phagocytes or macrophages | granuloma |
A form of coagulation necrosis | caseating |
A systemic disease of unknown origin characterized by granulomatous inflammation of the lung | sarcoidosis |
Systemic disorder involving multiple organ systems,Highest incidence in black women, Onset in the 3rd decade of life | sarcoidosis |
Elevated ESR, Leukopenia, Elevated ACE levels (40-80% prevalence) | sarcoidosis |
Requires tissue biopsy of a lymph node showing non-caseating granulomas | sarcoidosis |
Long-term corticosteroid therapy, ACE levels will tend to drop | treatment for sarcoidosis |
A condition characterized by the presence of vasculitis and granulomatous lesions affecting the respiratory tract and kidneys | Wegener’s Granulomatosis |
Small vessel vasculitis, Granuloma formation inflammation, Necrosis | triad of symptoms for Wegener’s Granulomatosis |
Nasal septum perforation, crusting and ulceration may present, Deep vein thrombosis and pulmonary emboli are common, “Saddle Nose” deformity is a late stage finding | Wegener’s Granulomatosis |
Idiopathic condition involving alveolar (lung) hemorrhage and rapidly progressive glomerulonephritis | Goodpasture's syndrome |
Most prevalent in men within the 3rd and 4th decade of life, Pathology is linked to glomerular antibodies | Goodpasture's syndrome |
Immunosuppressive Therapy is treatment for | Goodpasture's syndrome |