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Block II
Fluid & Electrolytes
The primary component of the body is | water |
Larger amount of body fat means | Lower amount of water content |
Older adults have | less muscle mass and more fat content which means less body water |
Fluid compartments in the body include | intracellular (inside the cells) and extracellular (outside the cells) |
ICF | Intracellular fluid 2/3 (40%) of body weight - adult |
ECF | Extracellular fluid |
ECF consists of the following | interstitial fluid (fluid in the spaces between cells), plasma (liquid part of blood), transcellular fluid (fluid contained within specialized cavities of the body) |
Amount of fluid secreted into and reabsorbed from the GI tract everyday | 3 to 6 liters |
Loss of fluids from vomiting and diarrhea concerns | serious fluid and electrolyte imbalances |
One liter of water weighs | 2.2 lbs (1kg) |
240 ml equals | 8 ounces |
Intake of 8 ounces equals | 0.5 lbs (0.23 kg) |
A loss of 4.4 lbs (2 kg) equals | 2 liters |
Electrolytes are | molecules that dissociate or split into ions when placed in water |
Cations | positively charged ions |
Anions | negatively charged ions |
Bicarbonate | HCO3 (negative) |
Chloride | Cl (negative) |
Phosphate | PO 4 3 (negative) |
Sodium | Na (positive) |
Potassium | K (positive) |
Calcium | Ca (positive) |
Magnesium | Mg (positive) |
Electrolytes are measured in | mEq |
Composition bewteen ECF and ICF is | approximately the same between the two compartments |
The main cation in ECF is | sodium with small amounts of potassium, calcium, and magnesium |
The primary anion in ECF is | chloride with small amounts of bicarbonate, sulfate, and phosphate |
The most prevalent cation in ICF is | potassium with small amounts of magnesium and sodium |
The most prevalent anion in ICF is | phosphate with small amounts of some protein and bicarbonate |
Normal Bicarbonate (HCO3 negative) - anion | 22 -26 |
Chloride (Cl negative) - anion | 96-106 |
Phosphate (PO 4 3 negative) - anion | 2.4 -4.4 |
Potassium (K) - positive cation | 3.5 - 5.0 |
Magnesium (Mg2) - positive cation | 1.5 - 2.5 |
Sodium (Na) - positive anion | 135 - 145 |
Calcium (Ca2) - positive anion (total) | 8.6 - 10.2 |
Diffusion | The movement of molecules from an area of high concentration to one of low concentration. |
Diffusion | The two areas must be permeable |
Diffusion | Requires no external energy |
Facilitated diffusion | Involves the use of a protein carrier in the cell membrane - the protein carrier combines with a molecule. |
Facilitated diffusion | Passive and requires no energy |
Glucose transport | An example of facilitated diffusion |
Active transport | A process in which molecules move against the concentration gradient |
Active transport | External energy is required |
An example of active transport is | The sodium - potassium pump |
Active transport - sodium moves out of the cell | Potassium moves into the cell |
Active transport's energy source is | Adenosine triphosphate (ATP) which is produced in the cell's mitochondria |
Osmosis | The movement of 'water' down a concentration gradient (from low concentration to high concentration) across a semi-permeable membrane. |
Osmosis | Requires no outside energy sources and stops when concentration differences equalize or hydrostatic pressure builds and prevents any further movement of water |
The greater the pressure (the higher the concentration) | The greater the solutions pulling - osmotic pressure |
Causes of increased venous pressure | Fluid overload, heart or liver failure, obstruction of venous return (blood flow back to the heart), venous insufficiency. |
Increased oncotic pressure results from |