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Chapter 8
Question | Answer |
---|---|
what are some of the viruses known to be linked to cancer | liver inf/hep/ebvirus/herpes/hpv |
cytoxic defined | chemicals that are toxic to cells, preventing their reproduction or growth |
antineoplastic defined | drug intended to inhibit or prevent the maturation and proliferation of neoplasms that may become malignant |
cycle-phase-nonspecific agents defined | agents that work on a cell at any time during the cells cycle |
5 types of cycle-phase-nonspecific agents | *nitrogen mustard*ethylenimines*alkyl sulfonates*triazenes*nitrosources |
cycle-phase-specific agents defined | agents work on a specific cycle during the cell cycle.used for rapid growing tumors |
name 5 types cycle-phase-specific agents | *carboplatin*cisplatin*ifosfamide*paclitaxel*mesna |
mutagenic defined | causes cells to mutate |
carcinogenic defined | causes cancer |
teratogenic | can cause birth defects |
BSC | biological safety cabinet |
what class BSC should chemo agents be prepared in | class II |
what are the 2 main differences of a BSC | *some are directly vented outside *others filter the air againbefore recirculatin |
BSC are validated every ____mos for integrity | 6 |
HEPA filters are recertified every _____________mos | 6/or if hood is removed |
shadowing defined | the act of blocking air flow in the BSC |
properly trained employees should have these requisites/knowledge when working with aseptic procedures(4)________,_________,___________,_________ | *proper training*compentency assessment*cont ed*recertification yrly |
teratogenic defined | tending to produce anomalies of formation |
aerosolization defined | suspension of small particles(liq or powder) in the air |
define permeability | property or state of being penetrable |
what are some of the risks assoc w/the handling of chemo drugs(2)_____________________,____________________ | *drug may get out of the container and in the air |
the drug may enter the handlers body thru (5) | inhalation,aborbtion,ingestion,accidental injection |