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Ch. 6
Drug Highlights
Term | Definition |
---|---|
Anit-inflammatory agent | relieves swelling, tenderness, redness, and pain of inflammation. can be classified as steroidal (corticosteroids) and non-steroids. |
Corticosteroids (glucocorticoids) | steroid substance with potent anti-inflammatory effects (ex: Depo-Medrol) |
Nonsteroidal Antiinflammatory Drugs (NSAIDs) | used in the treatment of arthritis and related disorders (ex: aspirin, ibuprofen) |
Disease-Modifying Antirheumatic Drugs (DMARDs) | can influence the course of disease progression; their introduction in early rheumatoid arthritis is recommended to limit irreversible joint damage (ex: gold preparation Ridaura) |
COX-2 inhibitors | Cyclooxygenase (COX) is an enzyme involved in normal cellular function and inflammation. COX-2 is found in areas affected by inflammation with OA and RA. Inhibition reduces production of compounds associated with inflammation and pain. (ex: Celebrex) |
Antitumor Necrosis Factor drugs (anti-TNF) | seem to slow/halt the destruction of joints by disrupting the activity of tumor necrosis factor (TNF), a substance involved in the body's immune response. (ex: Enbrel) |