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Gene Regulation

Introns are only found in Eukaryotic genes
DNA --> RNA --> Protein Central dogma of biology
Responsible for deacetylating histones Histone Deacetylase (HDAC)
Responsible for acetylating histones Histone acetyltransferase (HAT)
Control gene expression by regulating or inhibiting gene transcription Trancription factors
Achieved through regulating the enzymatic activity of HDAC and HAT Regulation of chromatin structure
Composed of capping, splicing, polyadenylation, and RNA editing RNA processing
What are the four elements found within an intron 5' 3' splice site, branch point, polypyrimidine tract
Can splicing be regulated Yes
Splicing regulated through the activity of SR proteins and hnRNP proteins
Alternative splicing is a way to increase protein diversity True
When iron levels are low ferritin mRNA is less stable True
When Iron levels are high ferritin mRNA is more stable True
When iron levels are low TfR (transferrin receptor) mRNA is less stable False
When iron leves are high TfR (transferrin receptor) mRNA is less stable True
Nonsense mediated decay is a pathway for regulating RNA degradation True
A paternal deletion of chromosome 15 q11-q13 Prader-Willi Syndrome
A maternal deletion of chromosome 15 q11-q13 Angleman syndrome
DNA methylation commonly occurs in ... regions of the promoter GC rich
DNA methylation is a method of turning off gene expression True
Created by: mhaynes