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Pharmacology Final
EVERYTHING
Question | Answer |
---|---|
zyrtec | cetirizine |
Zoloft | sertraline |
synthroid | levothroxine |
propulsid | cisapride |
procardia XL | nifedipine |
neurontin | gabapentin |
lasix | furosemide |
glucophage | metformin |
dilantin | phenytonin |
diflucan | fluconazole |
cardizem CD | diltiazem |
norvasc | amlodipine |
provera | medroxyprogesterone |
Xanax | alprazolam |
Lanoxin | digoxin |
sumycin | tetracycline |
bactroban | mupirocin |
BuSpar | Buspirone |
Zantac | ranitidine |
Cozaar | losartan |
aphthasol | amlexanox |
SingulAir | montelukast |
Lescol | lovastatin |
Coumadin | warfarin |
Biaxin | clarithromycin |
the federal trade commission does not allow false advertising of foods, OTC drugs and... | cosmetics |
a drug is first identified by its... | chemical name |
an ______ has an affinity for a receptor, combines with that receptor and produces an effect | agonist |
which route of administration is an injection in the gluteal mass or deltoid region? | intramuscular route |
what is defined as the amount of time that passes from the concentration of a drug to fall to one half of its blood level at any time? | half life |
name one factor that may alter drug effects | environmental |
tinnitus and hyperthermia are toxic reactions to high doses of... | aspirin |
which allergic reaction classification is demonstrated by symptoms of bronchospasm and laryngeal edema? | type I |
which route of administration may be used for the treatment of some forms of meningitis? | intrathecal |
in most states, before a dentist can legally write a prescription for a patient, what 2 criteria must be met? | patient of record must have a dental problem |
before this law, OTC mixtures could contain opium and cocaine | Harrison Narcotic Act |
when two drug formulations produce similar concentrations in _______ they are called biologically equivalent | blood and tissue |
what is another name for a trade name? | brand name |
what are the four main components of pharmacokinetics? | absorption, distribution, metabolism, excretion |
serum sickness is an example of a type what allergic reaction? | type 3 |
what is phase IV in Human studies of drugs | involves postmarketing surveillance |
what is the term for a genetically related abnormal drug response? | idiosyncratic reaction |
define the term ionic bond | two opposite charges are attracted to each other |
name one unit in the apothecary system | grain, scruple, ounce, pound, dram |
What goes in the superscription? | patient's name, address, and age date, the symbol Rx |
What goes in the inscription? | name of the drug, dose form, and the amount |
what goes in the subscription? | directions to the pharmacist |
what goes in the transcription? | signature directions to the patient |
a or a | before |
ac | before meals |
bid | twice a day |
c | with |
cap | capsule |
d | day |
disp | dispense |
gm | gram |
gr | grain |
gtt | drop |
h | hour |
hs | at bedtime |
p | after |
pc | after meals |
PO | by mouth |
prn | as required, if needed |
q | every |
qid | 4 times a day |
s | without |
sig | write (label) |
ss | one half |
stat | immediately (now) |
tab | tablet |
tid | three times a day |
ud | as directed |
a drug that acts at a location where norepinephrine is the neurotransmitter released is called | adrenergic |
cholinergic effects on the eye include... | myosis and cycloplegia |
what are adverse reactions of cholinergic agents when they are ingested in large doses? | salivation and lacrimation urination and defecation |
uses of anticholinergic agents do not include... | congestive heart failure |
gluconeogenesis is defined as.... | the formation of glucose from protein or fat |
uses of sympatheomimetic agents with respect to vasoconstriction include... | prolonged action hemostasis and decongestion |
what are functions of the autonomic nervous system? | blood pressure, heart rate, GI motility |
what describes Mydriasis? | dilation of pupil size |
what body part mainly releases epinephrine and some norepinephrine? | adrenal medulla |
phenoxybenzamine and phentolamine have been used in... | the treatment of Raynaud's and in the diagnosis of pheochromocytoma |
competitive neuromuscular blockers such as curare can cause... | paralysis of the small facial muscles and fingers loss of diaphragmatic breathing |
what is false regarding nicotine? | is not addicting |
the autonomic nervous system is made of the... | sympathetic nervous system parasympathetic nervous system |
beta adrenergic blocking agents can be used in the treatment of migraine headache prophylaxis....(T/F) | true |
Dantrolene is a drug use for the treatment of... | malignant hyperthermia |
succinylcholine when used with halothane can precipitate... | malignant hyperthermia |
B-1 receptors on the heart have.... | a postive chronotropic effect |
define efferent | |
what is cranial nerve VII called? | facial nerve |
which part of the ANS conserves body processes? | parasympathetic nervous system |
what are symptoms of pheochromocytoma? | tremors abdominal cramps |
what are ways to counteract xerostomia in dry mouth patients? | autonomic drugs, frequent sips of water, biotin mouth rinse |
MBD is an acronym for | |
BPH is an acronym for | benign prostatic hypertrophy |
dipivefrin is used in the treatment of... | glaucoma |
phenylephrine has been used in nose sprays to.... | decongest |
the perception component of pain is... | the physical component of pain and involves the message of pain that is carried through the nerves to the cortex |
nonopioids are also known as | peripheral |
what is false with respect to aspirin? | it can be applied topically to the oral mucosa |
near term high dose aspirin can lead to.. | prolonged gestation delayed parturition increased risk of hemorrhage in the mother and newborn |
what is not a symptom of salicylism? | appendicitis |
aspirin can interfere with the clearance of what medications and cause subsequent bone marrow suppression? | methotrexate |
NSAIDS inhibit ______ resulting in the decreased production of prostaglandin synthesis | cyclooxygenase |
what are oral adverse effects of NSAID | ulcerative stomatitis |
what due interactions with NSAIDS is incorrect? | may decrease the effect of digoxin |
codeine and detromethorphan are considered to be.... | antitussives |
what is true with respect to opioids? | they are useful in the treatment of diarrhea |
what are some symptoms of withdrawal? | tachycardia, rhinorrea, goose flesh, perspiration, lacrimation |
what is the prototype opioid agonist? | morphine |
what is used for the maintenance of the opioid free state in detoxified formally opioid dependent patients? | naltrexone |
most dental pain can be managed with the use of... | NSAIDS |
naloxone is the drug of choice for... | opioid overdose |
what are two shopper symptoms? | cancels dental appointments because of business trips or going out of town goes to several different dental offices because they "don't understand" |
opium is derived from the.... | poppy plant |
what does MAO stand for? | |
an excess of PG in the uterine wall producing painful contractions is known as... | dismenorrhea |
what is an NSAID dosed on an 8-12 hour schedule | Naproxen and Naproxen sodium |
alcoholics should avoid... | acetaminophen |
urate crystals are also known as | tophi |
what types of polyps are found in the aspirin hypersensitivity triad? | nasal polyps |
hepatotoxicity of acetaminophen is potentiated by the use of barbiturates, carbamazepine, phenytoin and... | rifampin |
What best describes the word bactericidal? | the ability to kill bacteria the effect is irreversible |
what is the best definition of the word iatrogenic? | practitioner can cause infection |
what dental procedure is infective endocarditis prophylaxis NOT recommended? | bleeding from trauma to the lips taking dental radiographs shedding of deciduous teeth |
what cardiac conditions require prophylaxis with dental procedures | prosthetic cardiac valve congenital heart disease cardiac transplantation recipients who develop cardiac valvulopathy |
vitamin K are... | oral coagulants so interfering with the production of vitamin K could increase the anticoagulant effect |
the use of clindamycin is linked with | pseudomembranous colitis |
what is the reason for antibiotic failure? | patient compliance wrong antibiotic poor debridement |
what is considered an adverse reaction of vancomycin? | red man syndrome |
how long is nystatin used for it to be effective? | 10-14 days or for 48 hours after symptoms have subsided and cultures have returned negative |
amino glycosides such as Kanamycin and Gentamicin have adverse reactions of ototoxicity and... | nephrotoxicity |
erythromycin is broken down... | in the gastric fluid and therefore must be enteric coated |
bactroban can be used for treatment of which condition? | impetigo |
neosporin is made up of.. | neomycin, polymyxin, bacitracin |
Diflucan is used to treat... | oropharyngeal and esophageal candidiasis |
photosensitivity, dizziness, vertigo, glossitis and chelitis are all adverse reactions to | tetracyclines |
define antiviral | suppress or retard the growth and multiplication of a virus |
the most common fungus in the oral cavity is... | candida albicans |
where are tetracyclines stored? | in the dentin and enamel of unerupted teeth |
what is one oral adverse reaction to tongue in the use of tetracycline | brown tongue |
name one oral reaction of the tongue in the use of metronidazole | black furry tongue |
what are the anti tuberculosis drugs? | Rifampin, INH, Pyrazinamide, ethambutol |
erythromycin increases the serum levels of theophylline, digoxin, triazolam, warfarin, carbamazepine and... | cyclosporine |
Griseofulvin is an anti fungal agent used to treat | ringworm of the scalp |
zidovudine (AZT) is a medication used to treat... | AIDS |
acyclovir is an.. | antiviral used to treat herpes simplex |
an adverse reaction of the quinolines is a rupture of the.. | achilles tendon |
what is one antibiotic agent in the lecture listed for non dental use | vancomycin |
minocycline can cause a _____ pigmentation of the mandibular and maxillary alveolar pne and hard palate | black |
what antibiotics can cause cardiac arrhythmias | cisapride and clarithromycin |
what is herpetic whitlow? | a prulent lesion which turns into an abbess at the bulbous long end of a finger |
reduction of simple anxiety and activity occurs with... | a small dose of a sedative hypnotic |
what has shown an improvement in sleep latency? | rozerem |
benzodiazepines facilitate _____ mediated transmission | GABA |
the use of benzodiazepines is contraindicated in... | narrow angle glauoma |
what is NOT a dental effect noted with the bezodiazepines | herpes labialis |
what is in FDA category X? | triazolam |
Benzodiazepines may increase the effect of phenytoin, digoxin and... | probenecid |
chronic long term use of barbiturates may lead to... | progressive depression psychologic dependence physical dependence |
what can be masked with flavored syrup? | chloral hydrate |
what drug may be used for the treatment of spinal cord injuries, cerebral palsy, multiple sclerosis and malignant hyperthermia? | dantrolene |
long acting barbiturates may be used fo | epilepsy |
what are some considerations for management of the dental patent taking benzodiazepines | all consent forms must be signed prior to taking medication patient must have a ride to and from the office do not drink alcohol or take opioids before taking benzodiazepines |
what are 5 symptoms of sloppy infant syndrome | hypoactivity hypothermia hypotonia feeding problems apnea |
what are 5 ways to manage sleep disirders | get out of bed if you can't fall asleep after 30 minutes drink a warm glass of milk, do not drink caffeine before bed try to keep regular sleep schedule do not smoke before bed |
what is a dermatologic effect of benzodiazepines | rash |
what is the side effect of first trimeter use of benzodiazepines? | cleft lip or palate |
what is one contraindication of the use of barbiturates | family history of parphyria |
what is one rationale in the use of analgesic sedative combintations | patient may need both a analgesic and a sedative |
what is the benzodiazepine antagonist? | flumazenil |
what is true regarding vitamin C? | a definite role in connective tissue metabolism required for the formation of collagen enhances the absorption of iron |
what is NOT an oral manifest ion of B1 deficiency? | dysqeusia |
a deficiency of which of what leaves the tongue a magenta red color? | riboflavin |
Wernicke's encephalopathy is a severe deficiency of | Thiamine |
a deficiency of this vitamin causes the tongue to appear smooth and slightly edematous, painful and purplish | vitamin B6 |
the use of which of the following several months before conception and in pregnancy prevent neural tube defects? | folic acid |
deficiency of which of the following can be induced by eating large quantities of eft white with symptoms of loss of appetite, mental depression and hypersthesia of skin | biotin |
which of the following has a deficiency characterized by nyctalopia, xeropthalmia and kertomalacia? | vitamin A |
which of the following is essential for the hepatic synthesis of clotting factors II,VII, IX, and X | vitamin K |
the basic function of this mineral involves the movement of oxygen and carbon dioxide from one tissue to another | iron |
what is NOT routine treatment manage of ANUG | biopsy |
dry socket is also known as.. | alveolar osteitis |
long term exposure to the sun is a possible cause of... | actinic cheilitis |
what is NOT associated with gingival enlargement | benadryl |
what is noted in acute toxicity of fluoride | profuse salivation and black stools |
which of the following is a natural product found in plants and inhibits biofilm attachment to the teeth | xylitol |
what has adverse effects of tooth staining, bitter taste, taste alteration, and increased calculus formation | chlorhexidine |
what are non pharmacologic therapies in the prevention of dental caries? | eat more products which stimulate saliva and are high in protein |
what is added to mouth rinses to decrease the number of microbes? | benzoic acid |
pilocarpine is... | a medication used to treat xerostomia |
for children under 2 years of age, clean teeth with soft cloth and massage the gums (T/F) | true |
floss teeth at least once a day (T/F) | true |
hormonal changes during pregnancy can cause gingivitis (T/F) | true |
the 0.2% form of chlorhexidine is used to kill S. mutans bacteria (T/F) | true |
fluoride gels are applied with toothbrush for 10 minutes or placed in a custom filled tray (T/F) | false |
What are the indications for dental treatment? | stable CHF |
what are the uses for digoxin? | treatment of CHF, atrial arrhythmias, atrial fibrillation, paroxysmal atrial tachycardia |
what are the oral side effects related to the use of digoxin? | increased salivation |
tetracycline and ______ can increase digoxin levels in 10% of patients | erythromycin |
what is true regarding amyl nitrate | volatile, no advantage for its use over nitroglycerin, not frequently used |
severe headaches, flushing, hypotension, lightheadedness and syncope are adverse reactions to... | nitroglycerin |
diziness, weakness, constipation, hypotension, dysgeusia and gingival enlargement are adverse reactions to | calcium channel blockers |
what is step II in the stepped care regimen of hypertension | therapy |
what is step I in the stepped care regiment of hypertension | life style changes |
which class of hypertension must be treated aggressively with antihypertensive agents | malignant |
losartan is considered the prototype.... | angiotension II receptor antagonist |
the most commonly used antihyperlipidemics are... | HMG-CoA reductase inhibitor |
what is not true when treating a patient taking warfarin | oral hygiene with sub gingival calculus removal can produce ageusia |
in the management of the dental patient taking hypertensives.... | avoid dental agents that add to side effects such as opiods |
what must you avoid in the dental patient taking nitroglycerin like agents | provide analgesic if headache occurs watch for syncope especially if rising avoid heat and moisture for proper storage |
what antihypertensive group is used for the treatment of an enlarged prostate | alpha 1 adrenergic blocking agents |
the centrally acting antihypertensive used as the drug of choice for a pregnant hypertensive women is... | hydralazine |
NSAIAs can decrease the antihypertensive effect of... | alpha 1 blockers angiotensin II receptor anatgonists ACE inhibitors |
what are the clot busters? | streptokinase |
what are indicated for intermittent claudication | pentoxyfylline |
if an NSAIA is to be used in a patient taking warfarin what can be prescribed to the patient | ibuprofen or naproxen |
NSAIAs can decrease the antihypertensive effect of... | alpha 1 blockers angiotensin II receptor antagpnists ACE inhibitors |
if an antibiotic is to be used with warfarin what has the greatest effect on changing warfarin's anticoagulant action? | erythromycin and metronidazole |
define automaticity | intrinsic rthym of the heart heart can regulate its own beat |
what is one clot buster | streptokinase |
what is one oral adverse effect of oral anticoagulants | petchia on the oral hard palate |
what are the characteristics of absence seizures? | breit loss of consciousness with little movement |
what characterizes grand map seizures? | urination, apnea and an epileptic cry may be present |
exfoliative dermatitis, erythma multiforme and drug induced lupus are... | idosyncratic reactions to anticonvulsants |
carbamazepine can be used to treat... | convulsions, trigeminal neuralgia, bipolar depression and chronic pain |
the pediatric dosage form of _______ has 63% sugar in it | carbamazepine |
the effect of carbamazepine may be increased by its use with | INH |
the most common barbiturate used in the treatment of epilepsy is... | phenobarbital |
what is NOT part of the fetal hydantonin syndrome? | thinning of the facial structures |
ethosuxamide is the drug of choice for the treatment of... | absence sizures |
as an adjunctive agent to treat absence seizures its oral effects include increased salivation, coated tongue, xerostomia and sore gums | clonazepam |
which precautions to be observed in the treatment of patients with mental disorders? | compliance, communication, suicidal tendencies |
irreversible dyskinesia of the tongue, lips, face and jaw is called | tardive dyskinesia |
what is true with respect to the use of tricyclic antidepressants? | 10% of the patients exhibit fine tremors |
prozac (fluoxetine) was was the first member of which group | serotonin specific reuptake inhibitors |
what can be used as an adjunctive in tobacco cessation? | wellbutrin |
MAO inhibitors may interact with amphetamines as well as foods and lead to... | hypertensive crisis |
in the management of the dental patient taking antipsychotic agents what is a consideration | check for xerostomia tardive dyskinesia may make oral hygiene more difficult epinephrine can be safely used in dental local anesthetic |
what is a consideration in dental management of the patient taking anticonvulsant agents | remove hands and dental instruments from mouth turn head to the side use additional CNS depressants cautiously |
some ______ can decrease the clearance of lithium | NSAIAs |
gingival enlargement is seen in ____% of all chronic users of phenytoin | 50 |
what are ways to manage phenytoin induced gingival enlargement | gingectomy, change medications, improve oral health |
what is one symptom seen in acute toxicity of tricyclic antidepresstans? | hypertensive crisis |
what is the prototype antipsychotic? | phenotonin |
what is a blood dyscrasias associated with Felbamate? | aplastic anemia |
carbamazepine can decrease the effect of... | doxycyline |
deloratidine (Clarinex) has the following side effects... | GI disturbance |
what is a mast cell stabilizer? | astelin |
histamine is useful in the diagnosis of... | pheochromocytoma |
what are the signs of toxicity with antihistamine use | death from coma with CV and respiratory collapse |
what is true with respect to the use of antihistamines? | can be used for vomiting induced by radiation therapy |
what can be used by injection to provide some local anesthesia? | benadryl |
erythromycin and ketoconazole ____ the level of fexofenadine | increase |
fexofenadine is also known as | allegra |
kinins aid in the mediation of | pulpal pain |
what substance is an example of a prostaglandin antagonist? | indomethacin |
what is responsible for stimulating gastric acid secretion? | H-2 receptors |
when an allergic reaction occurs the _____ degranulate and histamine is released | mast cells |
what is NOT usually seen in an anaphylactic reaction | hypertension |
what is NOT an H-1 receptor blocking effect | bronchodilation |
the drug of choice for anaphylaxis is... | parenteral epinephrine |
side effects of viral infections and drowsiness are noted in the use of | allegra |
which of the following was foun to cause cardiac arrhythemias | terfenadine |
cimeidine is used for the treatment of | GI problems |
PGEs stimulate the release of | GH, TSH, ACTH |
prostacyclin produced by blood vessel walls, inhibits | platelet aggregation |
prostaglandin ____ and prostaglandin ___ have an oxytocic action | E and F |
____ can cause secretion in the salivary glands and increases sodium and water excretion from the kidney | Substance P |
what are dental hygiene considerations in the management of patients using antihistamines | marked drowsiness may occur don't use alcohol with antihistamines remind patients caffeine may increase xerostomia |
what is NOT a pharmacologic effect of a glucocorticoid? | increased sodium retention |
what is NOT a characteristic of Cushing's syndrome | syncope and adrenal supression |
dental uses of corticosteroids do NOT include... | herpes labialis |
management of the dental patient taking steroids one must | give salicylates and NSAIAs with caution check blood pressure obtain good anesthesia |
adrenocorticoids are not secreted by... | the adrenal cortex |
what is NOT a characteristic of hypopituitarism | increased metabolism |
what is used to treat prolactin secreting adenomas, acromegaly and Parkinson's disease | bromocriptine |
what is NOT considered a systemic complication of diabetes | cystic fibrosis |
what is used to treat hypoglycemia in the early stages when the patient is awake | fruit juice, cake icing, glucose gel |
what is the prototype drug of the sulfonylureas | glyburide |
what drug classification slows down breakdown of ingested fat so that postprandial hyperglycemia is reduced | acarbose |
cloesevelam is a new | bile acid sequestrate |
what is secreted primarily by the ovaries but also by the testes and placenta | estrogens |
what is associated with estrogenic effects on the oral tissues | puberty gingivitis |
estrogens may be used to treat | menstrual disturbances |
what is an intraoral side effect of an oral contraceptive? | gingivits |
the use of androgenic steroids in females can cause... | virilization |
what hormones are secreted by the posterior pituitary? | vasopressin and oxytocin |
beta blockers are used to treat which of the following conditions encountered in hyperthyroidism | tachycardia |
Iodide in high concentrations can cause... | sialadenitis |
what is the rule of teo | patient taking 20 mg daily for more than 2 weeks, 2 years after dental treatment |
what are characteristics of hyperpituitarism | gigantism, large teeth, shedding of teeth |
what is another name for toxic nodular goiter | plumber's disease |
androgenic steroids are classified as schedule ____drug | 3 |
what is danazol? | treatment of endrometriosis and breast fibrosis |
antineoplastic drugs are... | designed to treat malignancies used to manage RA, and psoriasis |
which of the following is NOT of the reproductive cycle of a cell | K phase |
what is NOT classified of antineoplastic agents | antihistamines |
what are adverse dermatologic effects of antineoplastic drugs | exfoliative dermatitis |
what is considered to be environmental carcinogens | alflatoxins, PCBs from transformers, PCBs from transformers, benzene |
what are intraoral adverse effects of antineoplastic drugs | xerostomia, taste alteration, gingival bleeding, stomatitis |
what is de novo resistance? | cells have an innate resistance |
what is acquired resistance | cells that acquire resistance through mutation or natural selection |
adverse drug effects of the antineoplastic drugs on germ cells include... | inhibition of oogenesis |
according to the lecture handout, antineoplastic drugs can be used for the treatment of leukemias, choriocarcinomas, multiple myelomas and... | Brickett's lymphoma |
antibiotics are effective for the treatment of... | solid tumors |
estrogens are used in the palliative treatment of... | inoperable breast cancer |
plant alkaloids arrest cells in... | metaphase |
what is a stronger effect with an MDI than a comparable oral dose | bronchodilator |
dextromethorphan... | suppresses the cough reflex by direct effect on the cough center |
GERD symptoms are exacerbated by... | eating large meals, eating less than four hours before bedtime, lying flat on the bed without pillows |
what laxative classifications should one use caution in patients with renal impairment | osmotic saline laxatives |
what is the most common adsorbent combination in antidiarrheals is... | kaopectate |
what can be used to control nausea and vomiting associated with cancer chemotherapy | metocloparmide and cannabinoids |
COPD is divided into two groups... | emphysema and chronic bronchitis |
what is a side effect of albuterol? | tachycardia |
NSAIA-induced ulcers can be treated with | misoprostol |
blood levels of alcohol is higher in those taking... | cimetidine |
what is a systemic antacid? | sodium bicarbonate |
what extends through all the laters f the intestinal mucosa? | Crohn's disease |
symptoms of frequent urination, loss of appetite, nausea and vomiting, thirst, hypercapnia, warm and dry skin, rapid pulse and low BP are consistent with the condition of | diabetic coma |
symptoms of tachypnea, tachycardia anesthesia, nausea, faintness, perspiration, lightheadedness and shortness of breath are consistent with the condition of | hyperventilation |
symptoms of hyperpyrexia, increased sweating, hyperactivity, mental agitation, shaking, nervousness, and tachycardia are consistent with... | thyroid storm |
what is the drug of choice for opioid induced apnea | naloxone |
the treatment of parenteral hydrocortisone and oxygen by inhalation as well as fluid replacement after hospitalization is consisted for the condition of | acute adrenocortical insufficiency |
what is a level I or critical drug | epinephrine |
what is a level II drug | morphine |
the emergency hit should be checked every _____ to make sure drugs are not out of date | three months |
what is the local anesthetic of choice in pregnant women | lidocaine |
difficulty in lying prone and premature labor both characterize | the third trimester of pregnancy |
what analgesics are not recommended especially in the third trimester of pregnancy | aspirin and NSAIDS |
what are contraindicated during pregnancy | tetracyclines |
near term administration of _____ can produce respiratory depression in the infant | opioids |
what characterizes fetal alcohol syndrome? | microcephaly and micropthalmia, short palpebral fissures and flat maxilla, hypertonia and restlessness |
benzodiazepines are indicated in pregnancy for the treatment of... | status epilepticus |
what may increase the chance of kernicterus in the nursing infant | keoconazole |
large doses of what may be associated with fetal renal changes? | acetaminophen |
what is a known teratogen | lithium |