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Chapter 5
Therapy for fungal and viral infections
| Question | Answer |
|---|---|
| Single-celled organism similar to a human cell in that it has a defined nucleus | Fungus |
| A common target of fungal infections | Fingernails and toenails |
| A regimen of dosing one week per month, commonly used for treating fungal nail infections | Pulse dosing |
| This IV drug is used for blood-borne, life-threatening fungal infections. Prophylaxis with APAP and/or diphenhydramine and antiemetics is often necessary. | amphotericin B (Fungizone) |
| This drug is most often used in liquid form with the directions to "swish and swallow" to treat thrush or a yeastlike fungal growth in the mouth | nystatin (Mycostatin) |
| This antifungal capsule should be taken with pop or orange juice because absorption is improved by increasing stomach acidity | itraconazole (Sporanox) |
| This drug, an alternative to amphotericin B, can cause liver toxicity and blurred vision. | voriconazole (VFEND) |
| A minute infectious agent that is much smaller than a bacterium and cannot reproduce on its own | Virus |
| A virus that quickly resolves with no latent infection is known as this. An example is the common cold. | Acute viral infection |
| An infection that has a protracted course with long periods of remission interspersed with recurrence. An example is herpes. | Chronic viral infection |
| A drug that limits the progression of HIV or other retrovirus infections | antiretroviral |
| A drug that prevents HIV from entering the immune cells | fusion inhibitor |
| The ability of a virus to lie dormant and then, under certain circumstances, reproduce and again behave like an infective agent, causing cell damage | latency |
| The administration of antiretrovirals after exposure to HIV | post-exposure prophylaxis (PEP) |
| A compound that, on administration and chemical conversion by metabolic processes, becomes as active pharmacological agent | prodrug |
| A small lozenge | troche |
| Preventing infection by providing immunity | vaccination |
| Many antiviral drugs will end with this suffix | -vir |
| Many antifungal drugs will end with this suffix | -azole |
| This drug is can be used to treat influenza A and Parkinson's Disease. | amantadine (Symmetrel) |
| One of the first drugs, an NRTI, developed specifically for the treatment of HIV | AZT (Retrovir) |
| This NNRTI may induce vivid dreams, nightmares, and hallucinations, and has been abused for it's hallucinogenic properties | efavirenz (Sustiva) |
| Side effects associated with this class of HIV drugs include a redistribution of body fat, humped back, facial atrophy, breast enlargement, and hyperglycemia | Protease inhibitors |
Created by:
sarakiefer
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