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USMLE
Real Immuno 6 - Dzs by Hypersensitivity
Question | Answer |
---|---|
allergic rhinitis & anaphylaxis | type I |
hemolytic anemia | type II |
idiopathic thrombocytopenic purpura | type II |
erythroblastosis fetalis | type II |
rheumatic fever | type II |
Goodpasture's syndrome | type II |
bullous pemphigoid | type II |
Graves' dz | type II |
myasthenia gravis | type II |
SLE | type III |
rheumatoid arthritis | type III |
polyarteritis nodosum | type III |
post-strep glomerulonephritis | type III |
serum sickness | type III |
arthus reaction | type III |
hypersensitivity pneumonitis | type III |
type I diabetes mellitus | type IV |
multiple sclerosis | type IV |
Guillain-Barre syndrome | type IV |
Hashimoto thyroiditis | type IV |
Graft vs Host dz | type IV |
PPD (TB test) | type IV |
contact dermatitis | type IV |
IgM, IgG bind to Ag on "enemy" cell--> lysis or phagocytosis | type II (Ab-mediated) |
Ag-Ab complexes activate complement which attracts PMNs who release dangerous substances | type III (immune complex) |
sensitized T cells encounter Ag and release lymphokines to activate macrophages | type IV (delayed) |
fever, urticaria, arthralgias, proteinuria, lymphadenopathy 5-10 days after Ag exposure | (serum sickness) type III |