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3rd set
Question | Answer |
---|---|
Anti depressant drugs | block neuronal reuptake |
Anti depressant drugs are | Dopamine, Serotonin and Norepinephrine |
Biogenic Amine Theory of depression states that | there's Deficiency of Norepinephrine, serotonin and dopamine in CNS |
The tricyclic antidepressants are | Amitriptyline, Imipramine (Norepinephrine) - used for enuresis in children, attention deficit disorder, cocaine withdrawal patients. Desipramine, doxepin, Clomipramine (serotonin) - PTSD, PD, OCD. Nortriptyline, Protriptyline, Maprotiline, Amoxapine |
the tricyclic antidepressants | Block Neuronal re-uptake by increasing levels of norepinephrine and serotonin. the block histamine receptors, cholinergic receptors, Alpha - adrenergic receptors. |
the tricyclic antidepressants | increase mood, increase mental alertness, increase physical activity |
the Monoamine Oxidase Inhibitors are | Phenelzine, Tranylcypromine |
Monoamine oxidase Inhibitors | inhibit and prevent Inactivation of Norepinephrine, serotonin and Dopamine |
Monoamine oxidase inhibitors are | used for Severe depression |
MAO - A | handles excess Serotonin and Norepinephrine |
MAO - B | handles excess Dopamine |
Selective Serotonin Reuptake Inhibitors (SSRI) are | Fluoxetine (Prozac), Sertraline (zoloft), Paroxetine (Paxil), Nefazodone, Trazodone. Fluoxetine (Prozac) is used for Bulimia Nervosa Patients. Adverse effects of SSRI are Nervousness, Sexual dysfunction |
Anticonvulsants | 2 types of seizures are partial seizures and generalized seizures |
Partial seizures | No loss of consciousness |
Generalized seizures | Loss of consciousness |
Partial seizures | seen in one part of the brain. they are Simple partial and Complex partial |
Simple Partial | can occur at any age, does not spread, seen on single locus, no consciousness impairment. |
Complex partial | occur before age 20, consciousness Impairment, inability to carry out simple commands, lack of awareness of one's surroundings. |
Generalized seizure | seen in many parts of the brain. There's Tonic-clonic generalized (grand mal) and Absence Generalized (Petite Mal). |
Generalized seizure | Tonic clonic is most common,Absence is seen in kids btw 5-12 years,Myoclonic is rapid contraction of body muscles,Infertile spasms is bending of body at waist or neck,Status epilepticus is 30 min of continuous seizure,Febrile is convulsion by fever |
Anticonvulsant / Antiepileptic Drugs | Phenytoin, Carbamazepine, Valproic Acid, Ethosuximide, Benzodiazepines (Diazepam,Clonazepam,Clorazepate), Barbiturate (Phenobarbital,Primidone) |
Anticonvulsant / Antiepileptic Drugs | these drugs Inhibit Electrical Discharge and Spread of Discharge |
Phenytoin side effects are | Nystagmus, ataxia, gingival hyperplasia, megaloblastic anemia |
Carbamazepine side effect are | Blocks Na+ channels and its used in Partial epilepsy, Grand mal epilepsy, trigeminal neuralgia. Excess use can cause apalstic anemia, thrombocytopenia, Agranulocytosis, Liver failure, Spina bifida |