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Chapter 1
INTRODUCTION TO PHARMACOLOGY
Term | Definition |
---|---|
Absorption | The process by which a drug is taken into the body and moves from the site of administration into the blood. |
Adverse effects | Are undesired, potentially harmful side effects of drugs. They can include nausea and vomiting, drug toxicity, hypersensitivity, and unusual reactions. |
Agonist | Are drugs that bind to or have an attraction for a receptor and cause a particular response. |
Antagonist | Drugs that bind to a receptor and prevent a response. |
Bioavailability | Indicates the degree to which the drug molecule reaches the site of action to exert its effects. |
Biotechnology | Concepts of genetic engineering and recombinant DNA technology. |
Biotransformation | the chemical composition of a drug is changed by a process called metabolism. |
Bolus | Drugs that are given all at once. |
Contraindication | Reasons against giving a particular drug |
Distribution | The process in which drug molecules eventually diffuse out of the blood-stream to the site of action. |
Duration | The time between onset and disappearance of drug effects |
Emulsion | Type of liquid medication form and can be either water in oil or oil in water, depending on the medication’s solubility. |
Enteral | Indicates that the medication is taken into the gastrointestinal tract, primarily by mouth. |
Excretion | Medications taken into the body are eliminated in the process |
Hypersensitivity | An adverse effect resulting from previous exposure to the drug or a similar drug. |
Idiosyncratic effect | Type of adverse effect that is thought to occur in people with some genetic abnormality, causing either an excessive or an inadequate response to a drug. |
Indication | The reason or purpose for giving a medication. |
Local effect | Some topical agents work at the site of application. |
Onset | The time between administration of a drug and the first appearance of effects |
Parenteral | Any route other than the digestive tract, the most common of which are subcutaneous, intramuscular, and intravenous. |
Pharmacodynamics | The study of how drugs exert their effects on the body, at both the molecular and physiological levels. |
Pharmacokinetics | Focuses on how the body processes drugs. |
Plasma protein binding | Drug molecules that bind to proteins contained in plasma |
Reconstituted | Mixed with a liquid |
Side effect | A predictable but unintended effect of a drug. |
Solubility | Ability to be dissolved |
Solution | A mixture of drug particles |
Suspension | A mixture of drug particles fully dissolved in a liquid medium |
Synergist | A drug that enhances the effect of another drug |
Systemic effect | Medications that exert throughout the entire body |
Topical | Applied to the skin surface or a mucous membrane-lined cavity. |
Controlled substances | High abuse potential drug |
Narcotics | Is a controlled substance because they can be addictive and potentially abused |
DEA | Drug Enforcement Administration |
FDA | Food and Drug Administration |
The Joint Commission | The predominant standards-setting organization, and facilities that obtain its accreditation demonstrate their commitment to meeting certain performance standards. |
OTC | over-the-counter |
PDR | Physicians’ Desk Reference |
USP-NF | United States Pharmacopeia and National Formulary |