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Broncho/Leukotriene
1st year, 2nd semester nursing student, pharmacology test
Question | Answer |
---|---|
Bronchodilator/Leukotriene Antagonist montelukast | Singulair |
Bronchodilator/Leukotriene Antagonist zafirlukast | Accolate |
Bronchodilator/Leukotriene Antagonist zileuton | Leutrol, Zyflo |
Bronchodilator/Leukotriene Antagonist Indications | Prevention and treatment of asthma |
Bronchodilator/Leukotriene Antagonist Actions | Inhibit bronchocostriction by antagonizing the effects of leukotrienes |
Bronchodilator/Leukotriene Antagonist Contraindications | Acute asthma attack |
Bronchodilator/Leukotriene Antagonist Life Span | OB Lactation: satefy not established. Pedi: not established for <1 year |
Bronchodilator/Leukotriene Antagonist Drug interactions | Use of zafirlukast or zileuton with warfarin may increase PT Erythromycin and theophylline decrease bioavailability of zafirlukast. Montelukast has decreased bioavailability when taken concurrently with phenobarbital or rifampin. |
Bronchodilator/Leukotriene Antagonist Side Effects | Headache and dyspepsia most common Pedi: otitis and sinusitis |
Bronchodilator/Leukotriene Antagonist Implications and teaching | Montelukast- evening for asthma, any time of day for allergies. Have family and patient alert for agitation, panic attacks, depression, and suicidal thoughts. Zafirlukast- take on empty stomach due to food decreasing absorption. |