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phys neuro

QuestionAnswer
in the dark -retinal -[cGMP] -polarization -neurotransmitter 11-cis high [cGMP] depolarized glutamate released onto bipolar cells
in the light -retinal -[cGMP] -polarization -neurotransmitter all trans low [cGMP] hyperpolarized no neurotransmitter released?
pigments S-type:blue M:green L:red
dark adaptation (bright -> dark) breakdown of photopigments from light decreases photosensitivity slower than light adaptation
light adaptation (dark -> bright) rhodopsin broken down by bright light faster than dark adaptation
pathway of aqueous humor secreted by ciliary body -> travels around iris -> then to drainage canal glaucoma when too much aqueous humor
presbyopia cells in the middle of the lens die/become stiff, so can't accommodate for near vision; reading glasses
myopia eye too long/lens too strong
hyperopia eye too short/lens too weak
sensory transduction conversion of stimulus energy into a graded receptor potential
law of specific nerve energies nature of perception is defined by the pathway the info takes (ie spinal tract); origin is unimportant eg- press on eye, see stars
labeled line principle info enters spinal cord then EITHER enters reflex arc OR goes to brain for possible conscious awareness 1st order:afferent peripheral receptor 2: in spinal cord/medulla 3: thalamus
tonic receptor don't adapt eg-m. stretch, joint proprioception
phasic receptors rapidly adapt; slight depolarization "off response" when stimulus removed eg-touch receptors
receptive field varies with density of receptors in that region varied innervation importance of info
brain stem functions cranial nerves arise here control <3 rt, blood vessels, respiration, digestion regulate m. reflexes/posture RF gets and integrates all incoming info -RAS controls alertness
light -> deep/slow-wave sleep 30-40 min light, 30-40 min deep fastest EEG, lowest amplitude vitals same* as when awake, mental activity less visual, easily awakened excitatory neurons are inhibited by GABA
paradoxical sleep 10-15 min EEG looks like awake inhibition of m. tone, only eyes move, vitals irregular, dream involves visual processing, limbic, less activity in prefrontal ctx turn off slow-wave sleep on neurons
sleep control systems arousal system: RAS and hypoT (hypoT secretes hypocretin to stimulate RAS) slow-wave sleep center: inhibit excitatory neurons w/ GABA paradoxical sleep center: turn off slow-wave sleep on nuerons
dorsal columns conscious proprioception crossed touch, pressure, vibration
DSCT uncrossed conscious proprioception
VSCT crossed unconscious proprio
lateral STT crossed pain and temp
ventral STT crossed touch
lateral corticospinal tract crossed voluntary skeletal m.
rubro crossed involuntary skeletal m. (m. tone and posture)
ventral cortocospinal tract functionally crossed voluntary skeletal m.
vestibulospinal uncrossed involuntary skeletal m. (balance)
stretch/patellar tendon reflex stretch receptor in skeletal m. detects stretch the contraction of opposing m. is caused by monosynaptic reflex BUT an inhibitory interneuron in SC is also stimulated to inhibit the contraction, which is polysynaptic
basal nuclei functions inhibit m. tone in body select and maintain good stuff, suppress bad stuff coordinate slow sustained contractions (postural) linked to cerebral ctx and thalamus
thalamic functions part of diencephalon relay station, screens out un-important stufff positively reinforces voluntary motor behavior
habituation DECREASED responsiveness to repetitive presentations of an indifferent stimulus b/c less Ca2+ influx
sensitization INCREASED responsiveness to mild stimulus following a strong/noxious stimulus b/c interneurons secrete serotonin, which increases presynaptic cAMP, blocking K+ channels, so ap longer, so MORE Ca2+ influx
long-term potentiation involves AMPA and NMDA receptors
carebellum parts vestibulocerebellum spinocerebellum cerebrocerebellum
pitch discrimination where maximal deformation of basilar membrane tonotopic organization of brain
volume discrimination amplitude of vibration more frequent action porantials
utricle horizontal acceleration
saccule vertical acceleration
sympathetic neurons thoracolumbar short preggl fiber long postggl fiber ACh/nicotinic receptor at ggl NE and E/ alpha and beta receptors at target organ
parasympathetic neurons craniosacral long preggl fiber short postggl fiber ACh released onto nicotinic receptor @ ggl ACh released onto muscarinic @ target organ
alpha 1 most sympathetic target tissues constriction, increased secretion, etc. NE>E *nervous sweat
alpha 2 digestive organs decrease contractions NE>E
beta 1 heart increase rt and force of contractions E = NE
beta 2 smooth m. other than gut dilation, decreased secretion, etc. epinephrine ONLY
atropine blocks effect of ACh @ muscarinic receptors
Created by: jesters
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