Busy. Please wait.

Forgot Password?

Don't have an account?  Sign up 

show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.

By signing up, I agree to StudyStack's Terms of Service and Privacy Policy.

Already a StudyStack user? Log In

Reset Password
Enter the email address associated with your account, and we'll email you a link to reset your password.

Remove ads
Don't know (0)
Know (0)
remaining cards (0)
To flip the current card, click it or press the Spacebar key.  To move the current card to one of the three colored boxes, click on the box.  You may also press the UP ARROW key to move the card to the "Know" box, the DOWN ARROW key to move the card to the "Don't know" box, or the RIGHT ARROW key to move the card to the Remaining box.  You may also click on the card displayed in any of the three boxes to bring that card back to the center.

Pass complete!

"Know" box contains:
Time elapsed:
restart all cards

Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Urinary Tract Infect

Urinary Tract Infections

UTI Epidemiology ? * Community Acquired = more common in pregnant women and the elderly ...... * Nosocomial = 10% of cathed pts will receive one
Usu gram stain of men and women normal flora ? * Gram - staph and see strep too
Top Community Acquired Infections ? * Escherichia coli (80%) .... * The rest are -- Proteus-Morganella --- Klebsiella-Enterobacter --- Staphylococcus saprophyticus --- Enterococcus (Grp D strep)
E. Coli basics ? * Indole (+) --- Voges-Proskauer (-) --- Lysine decarboxylase (+) --- Lactose fermentation (+)
Nosocomial Infections ? * E. Coli = 20% ...... * the rest of the 80% is the same as Community
Host Defenses against UTI ? * IgA, pH, Prostatic fluid, micturition
E. coli Virulence Factors ? * adhere by fimbraie and P ..... * capsular polysaccharide.... * have hemolysins..... * resistant to serum bacterialcidal activity
E.Coli Patho ? * contamination and then adhere to uroepi. cells ... * see inflammation and hemolysis, with possible spread to kidneys
E. coli Virulence vs Host Defenses ? * The more compromised the host defenses, the less virulence required of E. coli to cause an infection
Female predisposing factors ? * spermicide use, anatomy, sexual activity, pregnancy
Both male and female factors ? * stones, urethral strictures , tumors, instrumentation (caths), and systemic diseases
dysuria and mucopurulent discharge caused by sexually transmitted agents ? * Urethritis - usu see gram (-) diplococci.... see Trichomonas vaginalis or even Chlamydia
dysuria, frequency, and urgency caused by multiplication of enteric organisms within the bladder ? * Cystitis - LN Strip (nitrite and leukocyte esterase) often used as a rapid screening test in physician’s office
fever, flank pain, and systemic signs caused by invasion of the kidney tissue by enteric organisms ? * Pyelonephritis - see WBC casts in UA
Asymptomatic Infections ? * can happen, and we usu see it in the elderly and only treat before a surgery or pregnancy
Uncomplicated Urinary Tract Infections ? * Patient has normal urinary tract without underlying disease - usu infected with E. Coli and in sexually active women
If a stone causes the UTI, what do we see ? * UA shows 75% are composed of a struvite-carbonate-apatite matrix and are are associated with urinary tract infections by urease-producing bacteria ---> Proteus mirabilis and Klebsiella
Getting a sample ? * clean and catch sample midstream for a UA or can insert a needle straight in to the bladder
Quantitative Culture ? * Media = Blood agar(red) or MacConkey (pink) agar...shows lactose fermenting pink or red colonies
Interpretation of Quantitative Culture ? * > 10n5 + WBC = acute pyelonephritis and cyctitis
Tmt of umcomplicated cystitis in women ? * short course (3 days) oral TMP/SMX or Nitrofurantoin...... * use FQ is resistant
Empiric treatment of acute uncomplicated pyelonephritis ? * Fluoroquinolone or 3rd gen cephalosporin (cefotaxime, ceftriaxone, or ceftazidime) ........ * base tmt off of UA/labs
Empiric treatment of complicated UTI ? * Moderately ill -- Fluoroquinolone ...... * Severely ill - Cefepime -- Ceftazidime -- Imipenem -- Piperacillin/tazobactam ...... * base drug tmt off of UA/labs
Prevention ? * urinate frequently, stay hydrated, pee after sex, shower..... * Cranberry Juice - actually contain that stop adherence of E.Coli, so can help
Created by: thamrick800