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Chemistry
toxicology and therapeutic drug monitoring
Question | Answer |
---|---|
Cannabinoids are found in | Marijuana |
When the rate of drug metabolism equals the rate of metabolism and excretion is known as | Steady state |
Peak levels of a therapeutic drug should be drawn _____ a dose | 1 hour |
Gentamicin and tobramycin are included in which class of therapeutic drugs? | Antibiotics |
Which therapeutic drug is associated with Red Man's Syndrome? | Vancomycin |
What is referred to as the date rape drug? | GHB |
Cyclosporine and tacrolimus are two therapeutic drugs commonly measured following an | Organ transplant |
Reyes syndrome in children and adolescents is a toxic effect of what drug? | Salicylate |
Theophylline belongs to which class of drugs? | Bronchodilators |
What drug is used to treat Bipolar disorder? | Lithium |
Which group of drugs are used to treat cold and allergy reactions? | amphetamines |
Which alcohol is converted to formaldehyde by the liver and can lead to death? | Methanol |
The first pass effect of drug metabolism occurs in which major organ in the body? | Liver |
What are some of the specimen requirements for alcohol toxicology testing? | Performed on plasma, serum, and whole blood Do not use alcohol prep pad Keep specimen capped |
What antipychotic drugs takes 2-4wks for the therapeutic effect to occur? | Doxepin and Imipramine |
What is the therapeutic drug monitoring? | The dose gives maximal therapeutic effect and the minimal toxic effect. |
Most drugs are bound to what in the body? | Proteins |
Digoxin belongs to what class of drugs? | Cardioactive |
Chronic toxicity | is due to repeated frequent doses over time |
Methods of alcohol testing | Enzymatic, gas chromatography, and Osmolarity |
Anti hypertensive drugs like sodium nitroprusside's primary role in treating high blood pressure. | dilate arteries and veins |
Group 1 analytes | Acetaminophen, Salicylate, Ethanol, and Carbon monoxide |
This synthetic substance is associated with toxic hepatitis, stroke, and MI | Anabolic steroids |
Aminoglycerides are used to | treat gram negative bacteria |
The distribution of an administered drug into interstitial and intracellular fluid depends on which physiological factors? | Blood flow, capillary permeability, binding of drugs to proteins, and tissue volume. |
Amphetamines are described as | Psychomotor stimulants that act by releasing monoamines from nerve terminals in the brain |
Drugs that bind to physiological receptors & mimic the regulatory effect of endogenous signaling compounds | agonists |
Elimination half life is | the time it takes for the amount of drug in the blood to reduce by 50% |
What type of drug is Tacrolimua? | Immunosuppressant |
What is the major organ involved in drug absorption | liver |