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Bacteria
pharmaceutically useful bacteria and their pharmaceutical relevance
Organism | Pharmaceutical relevance |
---|---|
Actinomyces spp. | Antibiotic production |
Bacillus atrophaeus | Validate and monitor dry heat and ethylene oxide sterilization processes |
Bacillus pumilus | Validate and monitor radiation sterilization processes |
Bordetella pertussis | Vaccine against whooping cough Causative agent of whooping cough |
Brevundimonas diminuta | 0.22-µm filter challenge test |
Clostridium sporogenes | Confirm anaerobic growth conditions |
Clostridium tetani | Vaccine against tetanus Causative agent of tetanus |
Corynebacterium diphtheriae | Vaccine against diphtheria Causative agent of diphtheria |
Escherichia coli | Kelsey-Sykes disinfectant capacity test Preservative limit test Food poisoning, severe enteritis |
Geobacillus stearothermophilus | Validate and monitor moist heat sterilization processes |
Haemophilus influenzae type b | Vaccine against Hib infections Causative agent of infantile meningitis and chronic bronchitis |
Leuconostoc mesenteroides | Dextran production |
Neisseria meningitidis | Vaccine against meningitis C |
Pseudomonas aeruginosa | Alginate production Kelsey-Sykes disinfectant capacity test General environmental contaminant Quintessential opportunist pathogen High resistance to antibiotics and biocides Biofilm-former |
Proteus vulgaris | Kelsey-Sykes disinfectant capacity test |
Salmonella enterica serovar Typhi | Chick Martin/Rideal Walker disinfectant coefficient test |
Staphylococcus aureus | Kelsey-Sykes disinfectant capacity test Preservative limit test Skin contaminant Food poisoning Toxic shock syndrome Pyogenic infections |
Bacteroides fragilis | Wound infections |
Campylobacter jejuni | Severe enteritis |
Legionella pneumophila | Causative agent of Legionnaire’s disease |
Mycobacterium tuberculosis | Causative agent of tuberculosis Disinfectant resistance Intracellular pathogen |
Salmonella spp. | Varying degrees of food poisoning, typhoid fever |
Staphylococcus epidermidis | Implanted medical device/prosthetic device contaminant Biofilm-former |
Streptococcus spp. | Causative agents of tonsilitis and scarlet fever |