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Leukemia
acute, chronic leukemia
Term | Conditions |
---|---|
M1 | Myeloblastic without maturation |
M2 | Myeloplastic with maturation |
M3 | Promyelocytic (APL) |
M4 | Myelomonoblastic |
M5 | Monoblastic |
M6 | Erythroblastic |
M7 | Megakaryoblastic |
Acute Leukemia | 50% of all leukemia |
Acute Myeloproliferative disorders | in Older adults |
Characteristics of acute leukemias | 25% or more blasts in peripheral blood; FAB classification 30% blasts in marrows; elevated WBC; Thrombocytopenia 80% pts anemia approx. 90% pts; superimposed infection; hemorrhagic phenomena |
Acute Leukemia Tx | to eradicate malignant clone & allow normal hematopoiesis to reestablish itself via chemotherapy |
Acute Leukemia Remission | 70 - 75% pts 12 - 16 months remission |
Acute Leukemia Survival | 25% with intensive tx |