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M6 13-005
Exam 16: MSK Drug Review
Question | Answer |
---|---|
What element is used to decrease inflammation in joints? | Gold |
What major side effect of Gold is exacerbated by sunlight? | Dermatitis |
What form of arthritis is where uric acid crystals accumulate in joint? | Gout |
What medication reduces production of uric acid thus decreasing amounts in joints? | Allopurinol |
what is Steven-Johnson Syndrome? | A serious and sometimes fatal cutaneous hypersensitivity reaction. |
What MSK drugs may cause Steven-Johnson Syndrome? | Allopurinol & NSAIDs |
What types of drugs are used to prevent and treat osteoporosis? | Bone Reabsorption Inhibitors |
Alendronate, Risedronate & Tilundronate are all examples of what? | biphosphonates |
What Bone Reabsorption Inhibitor acts like Estrogen? | Raloxifene |
What medication often given to patients with osteoporossis may inhibit biphosphonate absorption? | calcium |
What two serum labs are especially important to check on patients receiving alendronate? | serum calcium and serum creatinine. ? (Also Alkaline phosphatase in patients with Paget’s disease. Just sayin...) |
What are common side effects of bisphosphonates? | Bone pain, GI distress, nausea/diarhea and metallic taste in the mouth. |
When should you administer Alendronate po? | At least 30 minutes before meals with an 8 ounce glass of water. Have patient upright for at least 30 minutes to prevent GI distress (reflux). |
Why should patients on raloxifene stop taking their meds for prolonged periods of immobilization? | Increased risk of blood clots. |
Which class of anti-rheumatic drugs slow down joint destruction? | DMARDS (Eg. Enbrel and Remicade) |
Bacolefen, Fleceril, Valium and Paraflex are all examples of... | Muscle Relaxants |
Do not drive or perform any hazardous activity while on either of these medications | muscle relaxant or narcotic |
What natural hormone that has anti-inflammatory effects and can be given in a synthetic form | Corticosteroids |
What are side effects of Corticosteroids? | Hump back, moon face, weight gain, oily skin. |
What are dangerous or life threatening complications of steroid therapy? | osteoporosis, masking infection, diabetes and bleeding ulcers |
What serum electrolyte is most affected by steroids? | Serum Potassium |
What are the signs of adrenal insufficiency? | Hypotension, weight loss, muscle weakness, n/v, anorexia, lethargy, confusion, and restlessness. |
Which muscle relaxer acts directly on skeletel muscle? | Dantrolene |
What is Salicylism? | Dizziness, Tinnitus, Hyperventilation, Flushing, Sweating, Impaired hearing |
What are the three main actions of Salicylates, NSAIDs? | Antipyretic, Analgesic, Anti-inflammatory |
What is an analgesic? | Pain Reliever |
What are names of some common NSAIDs? | Ibuprofen, Celebrex, Vioxx, Motrin, Naprosyn |
Which non-narcotic analgesic does not have anti-inflammatories? | Acetaminophen (Tylenol) |
What non-narcotic analgesic has a major side effect of GI bleeding? | Salicylates |
Which Salicylate decreases the risk of MI and TIA? | Aspirin |
Which non narcotic analgesic has the major side effect of hepatotoxicity/hepatic failure? | Acetaminophen |
What syndrome is caused by giving salicylates to children with viral infections? | Reye's Syndrome |
Due to bleeding issues, do not take these 2 types of nonnarcotic analgesics together? | Salicylates and NSAIDS |
What are uses of narcotic analgesics? | Pain relief, severe cough, anxiety, sedation, detox |
What is the major side effect of narcotic analgesics? | Respiratory Depression |
Which medication reverses the respiratory depression of narcotic agents? | Narcan |