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M6 13-005

Exam 16: MSK Drug Review

What element is used to decrease inflammation in joints? Gold
What major side effect of Gold is exacerbated by sunlight? Dermatitis
What form of arthritis is where uric acid crystals accumulate in joint? Gout
What medication reduces production of uric acid thus decreasing amounts in joints? Allopurinol
what is Steven-Johnson Syndrome? A serious and sometimes fatal cutaneous hypersensitivity reaction.
What MSK drugs may cause Steven-Johnson Syndrome? Allopurinol & NSAIDs
What types of drugs are used to prevent and treat osteoporosis? Bone Reabsorption Inhibitors
Alendronate, Risedronate & Tilundronate are all examples of what? biphosphonates
What Bone Reabsorption Inhibitor acts like Estrogen? Raloxifene
What medication often given to patients with osteoporossis may inhibit biphosphonate absorption? calcium
What two serum labs are especially important to check on patients receiving alendronate? serum calcium and serum creatinine. ? (Also Alkaline phosphatase in patients with Paget’s disease. Just sayin...)
What are common side effects of bisphosphonates? Bone pain, GI distress, nausea/diarhea and metallic taste in the mouth.
When should you administer Alendronate po? At least 30 minutes before meals with an 8 ounce glass of water. Have patient upright for at least 30 minutes to prevent GI distress (reflux).
Why should patients on raloxifene stop taking their meds for prolonged periods of immobilization? Increased risk of blood clots.
Which class of anti-rheumatic drugs slow down joint destruction? DMARDS (Eg. Enbrel and Remicade)
Bacolefen, Fleceril, Valium and Paraflex are all examples of... Muscle Relaxants
Do not drive or perform any hazardous activity while on either of these medications muscle relaxant or narcotic
What natural hormone that has anti-inflammatory effects and can be given in a synthetic form Corticosteroids
What are side effects of Corticosteroids? Hump back, moon face, weight gain, oily skin.
What are dangerous or life threatening complications of steroid therapy? osteoporosis, masking infection, diabetes and bleeding ulcers
What serum electrolyte is most affected by steroids? Serum Potassium
What are the signs of adrenal insufficiency? Hypotension, weight loss, muscle weakness, n/v, anorexia, lethargy, confusion, and restlessness.
Which muscle relaxer acts directly on skeletel muscle? Dantrolene
What is Salicylism? Dizziness, Tinnitus, Hyperventilation, Flushing, Sweating, Impaired hearing
What are the three main actions of Salicylates, NSAIDs? Antipyretic, Analgesic, Anti-inflammatory
What is an analgesic? Pain Reliever
What are names of some common NSAIDs? Ibuprofen, Celebrex, Vioxx, Motrin, Naprosyn
Which non-narcotic analgesic does not have anti-inflammatories? Acetaminophen (Tylenol)
What non-narcotic analgesic has a major side effect of GI bleeding? Salicylates
Which Salicylate decreases the risk of MI and TIA? Aspirin
Which non narcotic analgesic has the major side effect of hepatotoxicity/hepatic failure? Acetaminophen
What syndrome is caused by giving salicylates to children with viral infections? Reye's Syndrome
Due to bleeding issues, do not take these 2 types of nonnarcotic analgesics together? Salicylates and NSAIDS
What are uses of narcotic analgesics? Pain relief, severe cough, anxiety, sedation, detox
What is the major side effect of narcotic analgesics? Respiratory Depression
Which medication reverses the respiratory depression of narcotic agents? Narcan
Created by: jtzuetrong