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OU autonomic drugs
autonomic drugs, classes, indication
drug | class | indication |
---|---|---|
bethanechol | cholinergic agonist (M) | ileus, urinary retention |
methacholine | cholinergic agonist (M & N) | Dx--bronchial hyperreactivity |
nicotine | cholinergic agonist (N) | (blank) |
pilocarpine | cholinergic agonist (M) | glaucoma (topical); xerostomia (oral) |
edrophonium | AChE inhibitor: reversible | Dx--myasthenia gravis (t1/2=10min) |
physostigmine | AChE inhibitor: reversible | glaucoma; antidote for atropine OD |
neostigmine | AChE inhibitor: reversible | myasthenia; reversal of nondepolarizing NM blockers |
echothiophate | AChE inhibitor: irreversible | organophosphate |
malathion | AChE inhibitor: irreversible | organophoshate |
parathion | AChE inhibitor: irreversible | organophosphate |
tacrine | AChE inhibitor | Alzheimer's (CNS entry) |
donezipil | AChE inhibitor: reversible | Alzheimer's (CNS entry) |
atropine | M blocker | antispasmodic, antisecretory, antidiarrheal, mgmt of AChE inhibitor OD |
tropicamide | M blocker | ophthamology (topical) |
ipratroprium | M blocker | asthma, COPD (inhalational)--no CNS entry or change in mucus viscosity |
scopolamine | M blocker | motion sickness, causes sedation and short-term memory block |
glycopyrrolate | M blocker | antispasmodic, antisecretory, antiulcer--no CNS entry |
benzotropine | M blocker | parkinsonism, drug-induced EPS--CNS entry |
trihexyphenidyl | M blocker | parkinsonism, drug-induced EPS--CNS entry |
hexamethonium | NN (ganglion) blocker | prototype, with no clinical use |
mecamylamine | NN (ganlion) blocker | severe HTN, for controlled hypotension during surgery, smoking cessation, Tourette's |