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MT Blood Bank
Study Questions for MT Blood Bank
Question | Answer |
---|---|
The interval between blood donations | 8 weeks |
The oral temperature of a donor must not exceed | 37.5 |
Minimum acceptable Hgb of fingerstick for male donor | 12.5 |
Lowest acceptable Hct by earlobe puncture fro female blood donor | 38% |
Prospective donors who have had malaria should be: | deferred for 3 years after cessation of treatment |
Donors who have been immunized with oral polio, measles or mumps vaccine and are symptom free are acceptable to donate after a period of | 2 weeks |
Which biochemical change does not occur in stored blood | pasma K decreases |
What is the acceptable temp range for a blood bank refrigerator | 1-6C |
If blood is to be transported, the blood temp must be kept between | 1-10C |
Which blood group system was discovered first | ABO |
What is an amorph | a gene with no observable effect |
Plasma form donors of what blood group can be transfused to an recipient | AB |
Which antibody is associated with Delayed Transfusion Reaction | Anti-JKa |
Naturally occurring antibodies are found regularly in which blood group system | ABO |
Characteristics of naturally occuring antibodies | React best in saline react best at room temp or 4C do not usually cross the placenta |
Immune antibodies may be produced by | intermuscular injection of blood pregnancy repeated blood tranfusions |
What is the dosage effect | Stronger reactions with homozygous cells than with heterozygous cells |
Anti-A1 is a seed extract from | Dolichos biflorus |
The frequency of Group A individuals in the US is | 41% |
Group B individuals | have anti-A in their sera |
Which blood group will not be agglutinated by Anti-A,B typing serum | 0 |
Which blood group reacts most strongly with anti_H | 0 |
What reagent is made from the seeds of the Dolichos Biflorus | anti-A1 |
Who proposed a numerical Rh Nomenclautre | Rosenfield |
What is a true characteristic of of Du | Du is a weak variant of the Rh0(D)antigen |
A Du of the gene interaction variety would have what genotype | DuCe/dCe |
What cells will Anti-C not react with | rr cells |
Anti E will react with | R2R2 Cells |
The f antigen refers to | ce |
The symbol for the Bombay blood group | Oh |
What antibodies will be detected in the sera of a Bombay Genotype | A,B,H |
Which system is composed of antigens found primarily in saliva and plasma | Lewis |
In the Duffy blood group which genes ar codominate | Fya and Fyb |
An acquired antibody | anti-Jka |
The antigen I is | absent on all cord cells |
Washed red cells tested with anti d and Rh control with a pos anti D and pos Rh control is most likely caused by | cells coated with immunoglobulin (pos DAT) |
What percentage of the population has the anti-Lea antibody | 1% |
What percentage of US caucasian population lacks the Kell antigen | 90% |
Anti-K does NOT react best | in saline at room temperature |
Anti K is also known as | anti-cellano |
what is the frequency of Fy(a-b-) in blacks | 68% |
What is the frequency of Fy (a-b-) in caucasians | very rare |
There is an association between the Fy(a-b-) phenotype and resistance to | malaria |
What percentage of males are Xga positive | 64% |
What percentage of females are Xga Negaive | 12% |
What color code is used for donor blood labels, Group A | yellow |
What is the standard acceptable color for anti A grouping serum | blue |
what is the color of dye added to commercially prepared antiB blood grouping serum | yellow |
Anti A1B serum confirms | Group O individuals |
What are suitable medium for suspension of red cells for BB | saline, serum, albumin |
What is NOT suitable medium for suspension of red cells for BB | distilled water |
What enzymes are used in BB procedures | ficin,bromelin,papain |
What enzyme is NOT used in BB procedures | amylase |
Enzymes prevent detection of antibodies in the? | Duffy System |
Elution? | The technique used to remove antibody bound to sensitized red cells |
The Donath-Landsteiner Test is associated with | PCH (parosysmal cold hemoglobinuria) |
A cold autoagglutinin will usually have specificity for the | I antigen |
PCH if often associated with antibodies of which system | P |
Forward grouping is | using known serum antibodies to detect unknown antigens |
Reverse grouping difficulties may be encountered in what instances | newborns, geriatric and chemotherapy patients |
Someone forward groups as an AB but reverse groups as B probably is a group A2B with | anti A1 |
The most dangerous antibodies in the blood bank are those that react at | 37C |
The best screening test for the detection of a large fetomaternal hemorrhage is | Erythrocye rosetting test |
The DAT using polyspecific combs sera is not of value in | differentiation of cell surface coating (complement or IgG) |
a Poly specific anti-human serum contains at lest antibodies to | IgG and C3d |
The DAT is most useful for? | HDN |
In a DAT you are testing | patient cells |
IDAT tests are used for? | detection of circulating antibody in patients serum |
when using chemically modified Anti-D, the recommended control is? | ABO grouping |
A false neg Antiglobulin test can be caused by? | inadequate washing |
What is the most common reason for mixed field agglutination | transfused cells mingling with patient cells |
the minor crossmatch | detects donor serum that react with recipient cells |
Which antibody is considered clinically significant | Anti-Kidd |
Which antibodies are usually considered clinically insignificant | anti-lea,anti-M,anti-P1 |
Which antibody is inactivated or destroyed by enzyme treatment | anti-Fya |
if a recipient is incompatible with only one donor, one should suspect | a recipient antibody to a low incidence antigen |
which antibody is present in 1:8 XM | anti-kell |
If a group O is xm for a group b recepient | the minor xm will be incompatible |
platelet concentrates are often used to treat patients with | thrombocytopenia |
cryoprecipitated AHF is not used to treat | Hemophilia B |
Deglycerolyzed frozen rbc must be transfused within how many hrs | 24 |
recurrent nonhemolytic febrile transfusion reactions are usually caused by | anti-HLA antibodies, platelet antibodies, white cell antibodies |
HDN can occur when | the lacks an antigen the infant possesses |
what antibody is most likely to be involved in HDN | anti-c |
when sever HDN is due to an unidentified antibody | the mothers rbc's may be used for transfusion |
which blood group has not been reported to cause HDN | P |
In case of HDN when the mother is O and the baby is A1, red cells for an exchange should be of what type | 0 |
in cases of ABO HDN the mother is usually what type | 0 |
what percentage of donor blood test would be compatible of an anti-e transfusion | 2% |
what percentage of donor blood is compatible with a patient who has anti-jka | 25% |
to find two units of compatible blood for a patient who has anti-jka how many units will have to be crossmatched | 10 |
A 56C water bath is commonly used for | preparing eluates, inactivating sera |
testing media for antigen/antibody reactions include | isotonic saline, LISS, albumin, enzymes |
Anti A1 agglutination is found | occasionally in A2 pts and group b and o pts |
weak agglutination with anti A sera is to be expected with which blood groups | A2 and A2B |
weak agglutination with anti-A sera can be expected with | A2 and A2B groups |
Anti-A1B is obtained from | is obtained from group o individuals and also confirms group o individuals |
Rh antibodies | react more strongly at 37C than at 4C are acquired from transfusion or pregnancy can cross the placenta |
Which antibodies are naturally occuring | anti P1, anti Lea, anti-S |
in a very acute phase of hepatitis, what would indicate an onset of a viremic state | positive HBSAg |
what is the expiration date of RBC preserved with citrate-phosphate-destrose adenine(cpda-1) | 35 days |
LISS | causes decrease in electropositive catiosn surrounding RBC usually consists of phospate saline and glycine enhance the rate and sensitivity of antigen antibody reactions |