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IBD
Inflammatory Bowel Disease
Characteristic | IBD |
---|---|
Disordered response to intestinal bacteria | Crohn's |
Autoimmune etiology | Ulcerative colitis |
Rectal sparing | Crohn's |
More commonly involves ileum | Crohn's |
Skip lesions | Crohn's |
Continuous lesions | Ulcerative colitis |
Rectal involvement | Ulcerative colitis |
Cobblestone mucosa | Crohn's |
Transmural inflammation | Crohn's |
Mucosal & submucosal inflammation only | Ulcerative colitis |
Friable pseudopolyps with freely hanging mesentery | Ulcerative colitis |
Creeping fat | Crohn's |
String sign on barium swallow | Crohn's |
Lead pipe appearance due to loss of haustra | Ulcerative colitis |
Linear ulcers, fissures, and fistulas | Crohn's |
Right lower quadrant pain | Crohn's |
Left lower quadrant pain | Ulcerative colitis |
NOD2 mutation association | Crohn's |
Noncaseating granulomas | Crohn's |
Lymphoid aggregates | Crohn's |
Crypt abscesses | Ulcerative colitis |
Ulcers and bleeding without granulomas | Ulcerative colitis |
Th1-mediated response | Crohn's |
Th2-mediated response | Ulcerative colitis |
Perianal disease | Crohn's |
Primary sclerosing cholangitis | Ulcerative colitis |
Toxic megacolon | Crohn's |
Bloody diarrhea more common | Ulcerative colitis |
Migratory polyarthritis | Crohn's |
Erythema nodosum | Crohn's |
Pyoderma gangrenosum | Ulcerative colitis |
Sometimes p-ANCA positive | Ulcerative colitis |
Renal calculi | Crohn's |
Recurs after surgery | Crohn's |
Treated with colectomy | Ulcerative colitis |
Collections of neutrophils within crypts of Leiberkuhn | Ulcerative colitis |
Regional enteritis | Crohn's |