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GowFundsII

Chapter34 Drugs to treat disorders of Musculoskeletal System

QuestionAnswer
RA- Rheumatoid Arthritis chronic inflammation of connective tissue
Osteoarthritis Non-inflammatory degeneration so articular cartilage and change in the synovial membrane
Bone resorption inhibitors bisphosphonates
Bone resorption inhibitors USE Osteoporosis in post menopausal women and men. hypercalcemia of malignant disease and Paget's disease of the bone
Examples of Bone resorption inhibitors Fosamax, Boniva, Actonel
Adverse Reactions of Bone resorption inhibitors Nausea diarrhea, acid regurgitation, increased or recurrnet back pain, dyspepsia
Adminstration guidelines for bone inhibitors empty stomach, have to sit up for 30 minutes
Bone resprtion inhibitors contraindication delayed esophageal emptying or renal impairment & hypersenstivey
DMARD For Rheumatoid Arthritis-sulfa based drug
Adverse Reaction DMARD Nausea, stomatitis, alopecia,
Methotrexate watch for bruising (thrombocytopenia) Infection (leucopenia)
Examples of DMARD Plaquenil, Remicade, Enbrel, Imuran, Cytoxan, Humira
Gold is the last result! Watch for what? mouth ulcers, Give good oral care!
Uric acid inhibitors Managing and preventing acute attacks of gout
Gout A form of arthritis in which uric acid accumulates in the blood and is often deposited in the joints
Adverse Reactions of Uric Acid Inhibitors GI reactions N/V & diarrhea
Zyloprim (allopurinal) Reduces uric acid production (chronic use)
Cholchicine Reduces inflammation for acute attacks
Probenicid Prolong plasma levels of penicillin
Adminstration Guidelines for Uric Acid inhibitors With meals/food or immediately after eating
Crystralluria Crystals in urine
What to watch for with crystalluria kidney stones
pts with crystalluria should? drink 1000-2000ml of fluids a day
Skeletal Muscle Relaxants Use:various acute painful muscle spasm, lumbar strains, cervical strain, neck back pain
Adverse Reaction of Skeletal Muscle Relaxants #1 is drowsiness
Flexeril (cyclobenzaprine
Valium causes Drowsiness, sedation,
Be careful with MAOI use. Why? Can excatrabate Psychosis
Created by: tsgfw
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