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Immunity

QuestionAnswer
Immunity INNATE IMMUNITY
What is Immunity? Ability to resist damage from foreign substances as microorganisms and harmful chemicals
Innate Immunity -Innate or nonspecific resistance =Mechanical mechanisms: Prevent entry or remove microbes =Chemical mediators: Promote phagocytosis and inflammation -Cells: Involved in phagocytosis and production of chemicals
Adaptive or specific immunity Specificity: Ability to recognize a particular substance Memory: Ability to remember previous encounters with a particular substance and respond rapidly
Inflammatory Response --Tissue injury regardless of type can cause inflammation Response initiated by chemical mediators that produce vasodilation, chemotactic attraction, increased vascular permeability Types -Local: Symptoms are redness, heat, swelling, pain, loss of functn -Systemic: Symptoms are increase in neutrophil numbers,
Innate Immunity: Cells -White blood cells Most important cellular components of immune system -Methods *Chemotaxis *Phagocytosis *Neutrophils -Phagocytic and first cells to enter infected tissue
Innate Immunity Cells II -Macrophages -Monocytes that leave blood, enter tissues -Large phagocytic cells -Basophils and mast cells >Promote inflammation -Eosinophils >Reduce inflammation -Natural killer cells >Lyse tumor and virus-infected cells
Antigenic Determinants -Antigenic determinants =Specific regions of a given antigen recognized by a lymphocyte -Antigenic receptors =Surface of lymphocyte that combines with antigenic determinant
Created by: zeenat
 

 



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