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Pharmacology Nurses
Chapter 22 Drugs for Lipid Disorders
Question | Answer |
---|---|
Three Types of Lipids | Triglycerides, Phospholipids, Steroids |
Cholesterol | 1.The most widely known of the steroids 2.Promotes Atherosclerosis 3.Serves as the building block for a number of essential biochemicals, including vitamin D, bile acids, cortisol, estrogen, and testosterone. 4. Excretion via bile only way of removal. |
Total Cholesterol | < 200 = Desirable 200-239 = Borderline High Risk > 239 = High Risk |
The American Heart Association recommends: | less than 300 mg of dietary cholesterol per day. |
Lipoproteins | Lipid molecules are not soluble in plasma to transport the body forms complexes called lipoproteins, that have a protein carrier (apoprotein) |
HDL (High Density Lipoprotein) (HAPPY) | 1. contains the most apoprotein 2. manufactures in the liver and small intestine and assist in the transport of cholesterol away from the body tissues (reverse cholesterol transport) <40 = LOW 40-59= Borderline High Risk >60 = Desirable |
LDL (Low Density Lipoprotein) (LAME) | Contains the highest amount of cholesterol < 100 = desirable 100-129 = near above optimal 130-159 = Borderline high risk 160-189 = High Risk >190 = Very High Risk |
VLDL (very Low Density Lipoprotein) | Through a series of steps, VLDL is reduces in size to become LDL. is the primary carrier of triglycerides in the blood. |
Hyperlipidemia | High Levels of lipids in the Blood, a major risk of cardiovascular disease. |
Hypercholesterolemia | 1.Elevated blood cholesterol. 2.Type of Hyperlipidemia |
Dyslipidemia |