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Chpt 33 interations
Antihistamine Interactions
interacting drug | Effect of interaction |
---|---|
rifampin | May reduce the absorption of the antihistamine (e.g. fexofenadine) |
MAOIs | Increased anticholinergic and sedative effects of the antihistamine |
CNS depressants (e.g. opioid analgesics or alcohol) | Possible additive CNS depressant effect |
Beta blocker | Risk for increased cardiovascular effects (e.g. w/ diphenhydramine) |
al- or mg-based antacids | Decreased concentrations of drug in blood (e.g., fexofenadine) |