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Path 25
Toxicology
| Question | Answer |
|---|---|
| How are "screen positive" results confirmed | GC/MS (Gas Chromotography - Mass Spectrometry |
| When should you order a drug level | 1) suspician of noncompliance, individual patient variation, altered drug utilization, compensation for an altered physiological state, drug interactions |
| What are some means of direct removal of the toxin | emesis, whole bowel irrigation and stomach lavage, hemodialysis/hemoperfusion, activated charcoal |
| When do you need to give thiamine | with chronic or acute ethanol use |
| What do you give to reverse dysrhythmias and hypotension in patients who fail to respont to atropine, epinephrine, dopamine etc. following beta-blocker, or calcium channel blocker induced bradycardia adn hypotension | glucagon |
| what do you give to clear the body of methemoglobin | methylene blue |
| What adrenergic effect does Clonidine have | Alpha-2 adrenergic agonist |
| Hyperbaric oxygen is useful with what type of poisoning | CO |
| CaEDTA is an atidote for? | lead |
| 2,3 dimercaptosuccinic acid is an antidote for? | lead, arsenic, mercury |
| Naloxone reverses the effects of ? | opiates and propoxyphene |
| N-acetylcystein is thought to work by? | replenishing glutathione levels thus preventing liver damage following acetaminaphen overdose |
| What can you give with methanol poisoning | ethanol (favored by liver enzymes over methanol) |
| What does 4-methylpyrazole do? | specific inhibitor of alcohol dehydrogenase that has a higher affinity for the enzyme than methanol and ethylene glycol reducing production of toxic metabolites |
| What should you give to anemic patients taking isoniazid | pyridoxine |
| What should you give to reverse the effect of acute anticholinergic poisonings by binding to Ach | Physostigmine |
| what is a cholinesterase reactivator that reverses the inhibitory effect on the enzymes by organophosphate pesticides | pralidoxime |
| What is the specific benzodiazepine receptor antagonist that reverses the effects of both long and short acting benzodiazepines | flumazeni |
Created by:
UVAPATH1
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