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Lecture 7
Intestinal Protozoa - Amoeba
| Question | Answer |
|---|---|
| What is the definition of dysentery | diarrhea with gross or occult blood in stool |
| What is considered persistent diarrhea? | >= 14 days |
| what is the peak age of incidence in developing countries? | 6-11 months of age |
| What is the definition of diarrhea? | 3 or more liquid stools within 24 hour period (not including breast-feeding babies) |
| true/false: diarrheal and respiratory diseases are the leading causes of deaths in the developing world | true: 3.2-3.5 million/year! |
| How often are the etiologic agents for diarrhea identified? | <60% of the cases |
| What three known parasites cause diarrhea? | Giardia lamblia, Cryptosporidium parvum, Entamoeba histolytica |
| Which parasite is a major cause of diarrhea in patients with AIDS? | Cryptosporidium parvum |
| What three invasive diseases in addition to diarrhea does Entamoeba histolytica cause? | dysentery, colitis, liver abscess |
| What are 5 risk factos for amebiasis? | 1.hispanic/asian/pacific islander (50% of reported cases) 2. travelers 3. institutions for mentally retarded 4. Men who have sex with men 5. male (90% amebic liver abscesses are in men) |
| What are the symptoms of amebic colitis? | 1. symptoms greater than 1 wk. 2. diarrhea 3. heme + stool 4. weight loss 5. fever >38 C |
| Why is diagnosis of Entamoeba histolytica difficult? | Microscopy cannot distinguish betw. E. histolytica and E. dispar and E. moshkovskii which are nonpathogenic |
| Which is the most sensitive and specific way to diagnose amebic colitis? | Stool antigen test |
| Who is more likely to get amebic liver abscess, males or females? | Males:females 10:1 |
| What are the symptoms and labs abnormalities in amebic liver abscess? | symptoms greater than 4 wks, diarrhea, fever, right upper quadrant pain, leukocytosis, anemia abnormal liver enzymes, elevated bilirubin |
| What is the most sensitive method for detecting amebic liver abscess? | Serum Antigen (unlike with colitis) |
| What is the tissue active agent for amebiasis? | Metronidazole or tinidazole or ornidazole |
| What is the luminal agent for amebic colitis? | paromomycin |
Created by:
UVAPATH4
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