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Immune System
Question | Answer |
---|---|
nonspecific defense mechanisms | physical barriers (unbroken skin), natural deterrents (fluids and cells), infammatory response |
specific defense mechanisms | antibodies and complements |
two forms of immunity | natural and acquired |
natural (inante) immunity | not for certain disease, no prior exposure |
natural immunity example | macrophage |
two types of acquired immunity | passive and active |
passive aquired immunity | protective substances from human or animal |
passive aquired immunity examples | breast milk and antitoxins |
active aquired immunity | direct exposure, stimulates immune response |
active aquired immunity examples | vaccines and chicken pox |
antigens | disease causing agents |
two types of immune responses | humoral (antibody-mediated) and cellular (cell-mediated) |
humoral immunity | production of B lymphocytes, produce antibody, antigen-antibody complex, phagocytosis |
antigen-antibody complex | antibodies combine with antigens |
cellular immunity | produces T cells and NK cells, cytotoxic |
cytotoxic | toxic to cells |
bacteria | unicellular, prokaryotic microorganisms |
bacteria shape | round, rod, spiral |
most common organism on planet | bacteria |
g- bacteria | more substantial cell wall, gram stain does not enter cell |
g+ bacteria | less substantial cell wall, gram stain enters cell |
which bacteria are easier to treat | g+ |
bacteriostatic drugs | prevent replication |
bacteriocidal drugs | kill bacteria immediately |
superinfection | infection following a previous infection from resistant microorganisms |
parasites | multicellular or single-celled, not bacteria or fungi |
parasitic relationship | asymmetrical symbiotic (benefits from host, host has no benefit or is harmed) |
most common parasites | pinworms, roundworms, tapeworms |
parasite transmission | through contaminated food or soil |
virus | ultramicroscopic infectious pathogen |
virus replication | within cell of a living host |
what drugs are ineffective for viruses? | antibiotics |
fungi | plant based, yeasts, molds, mildews |
fungi replication | through spores |
antivirul drug examples | acyclovir, valacyclovir |
antifungal drug use | therapy of systemic or topical yeast infections and superficial fungal infections |
antifungal drug example | fluconazole |
most common HIV | HIV-1 |
HIV transmission | sexual contact, body fluids, birth from mother to child |
AIDS | Aquired Immune Deficiency Syndrome |
Stage 1 of AIDS | initial transmission/infection |
Stage 2 of AIDS | immune system suppressed |
Stage 3 of AIDS | signs/symptoms appear |
Stage 4 of AIDS | opportunistic infections lead to CD4 cell count or level below 200 in blood |
Stage 5 of AIDS | wasting to death |
example of autoimmune disease | Lupas |
antibiotic adverse effects | gastrointestinal distress, yeast infections, hypersensitivity reactions |
hypersensitivity reactions | release of histamine, rash-wheezing-SOB-anaphylactic shock |
beta lactam antibiotics | penicillin binding proteins in bacteria cell walls |
penicillin side effects | increased bleeding and bruising |
penicillinase | resistant bacteria enzyme that breaks down penicillin |
Penicillin G | first generation, not prescribed now, bacteriocidal |
Penicillin VK | bacteriocidal, amoxicillin |
cephalosporin antibiotics | similar to penicillin, grouped in generations 1-5 |
cephalosporin drug examples | keflex, ceftin, cefzil |
macrolide antibiotics | new, bacteriostatic |
macrolide antibiotic drug examples | erythromycin, azithromycin, clarithromycin |
erythromycin adverse effects | ototoxicity, liver disfunction, colitis |
azythromycin | long 1/2 life, treats lyme disease |
aminoglycoside antibiotic function | inhibit protein synthesis, bacteriocidal |
aminoglycoside adverse effect | ototoxicity, respiratory paralysis, deafness in children |
ear infection medicine | Cortisporin Otic |
eye infection medicine | TobraDex |
tetrcycline antibiotics adverse effects | photosynthesis, cant be taken with food, milk, bone formation disruption |
doc for intracelluar infections | tetracycline antibiotics |
minocycline | most active tetracycline, treats meningitis and rheumatoid arthritis |
sulfa antibiotics | treats kidney infections |
sulfa antibiotic adverse effect | must drink water |
quinolone antibiotic function | prevent bacteria DNA from unwinding and duplicating |
quinolone antibiotic contraindications | antacids |
drug resistance | a microorganisms ability to live and grow in the presence of an intiinfective or antimicrobial drug, result of genetic mutation |
how to prevent antibiotic resistance | avoid unnessecary use in humans and animals, use most specific antibiotic, no leftover pills |