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phase 2 met path
phase 2 metabolic pathways
Question | Answer |
---|---|
glucuronidation | conjugating agent: glucuronic acid high energy intermediate: UDPGA functional groups:-OH, -COOH, -NH2, -SH |
Sulfation | conjugating agent:sulfate high energy intermediate: PAPS functional groups:-OH, -NH2 |
Amino acid conjugation | conjugating agent: Glycine high energy intermediate: Coenzyme A thioesters functional groups:-COOH |
Acetylation | conjugating agent: Acetyl CoA high energy intermediate: Acetyl CoA functional groups:-OH, -NH2 |
Methylation | conjugating agent: CH3 from S-adenomethionine high energy intermediate: S-adenomethionine functional groups: -OH, -NH2 |
Glutathione (mercapturine acid conjugation) | conjugating agent: glutathione high energy intermediate: arene oxides, epoxides functional groups: Aryl halides, epoxides, arene oxides |