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Accessory Glands SG
Accessory Glands
Question | Answer |
---|---|
Parotid Gland | 2 of them. Major salivary gland. Long duct that secretes saliva into oral cavity. Covered with a connective sheath. Consist of serous acini |
Submandibular gland | Long duct that sends saliva into oral cavity. mixed glands |
Sublingual gland | Within the oral cavity has a series of short ducts that secrete saliva into oral cavity. Mucous acini |
Saliva contents | Enzymes like amylase and lipase which initiates digestion of ingested carbs and lipids. IgA which attacks bacteria. Lactofernin: deprives bacteria of iron |
Basket cells | Form a basket around the acinar and they have contractability so they squeeze it out |
Interculated ducts connecting to striated ducts | Folding of basement membrane, and mitochondria which increases surface area for transport so as saliva passes through it can be reconstituted |
Liver Endocrine | Synthesizes and secretes blood proteins. Includes albumin, prothrombin, and fibrinogen and lipoproteins |
Liver Exocrine | Secretes bile, phospholipids and cholesterol are in bile, bile is ejected into common bile duct and travels to duodenum. |
Space of Mall | Place where tissue fluid can collect and lymph can form |
Space of Disse | Substances can travel from one capillary into the space where it encounters the membranes of the hepatocytes and transport can occur into hepatocyte and vice versa |
Portal vein and central vein | Portal vein carries majority of blood. Central vein carries blood back by hepatic vein |
Kupffer cells | Macrophages that live in the sinusoids of liver that eat aged erythrocytes |
Lipoproteins | Chylomicrons are lowest density. LDL= bad cholesterol. HDL=good cholesterol. HDL leaves the liver with no cargo and finds its way around the circulatory system and sops up cholesterol and delivers it back to liver |
Cystic duct | Reprocessed and concentrates bile so that the water and salt are removed and concentrated about 10 times |
CCK | After a meal CCK encounters the masculature of the gall bladder and forces the bile out through the cystic duct and common bile duct |
Gallbladder epithelium | Mucosa is highly folded which allows for distention of the wall. Columnar epithelium. No muscularis mucosa, no submucosa. Has muscularis externa only. |
Gallbladder sodium transport | Transported from the cytosol into intracellular space between adjacent epithelial cells. |
Gallbladder neutrality maintainance | Electric neutrality: Cl follows Na. Osmotic neutrality: Water follows salt into the space. There are occluding junctions so fluid cannot flow back into lumen |
Endocrine Pancreas | Islets of Langerhands: A=secrete glucagon, B=secrete insulin, D=secrete somastatin, F=secrete polypeptide |
Insulin synthesis and secretion | rER as preproinsulin-signal peptide cleaved in rER-proinsulin is transported to golgi-insulin and connecting peptide is stored in vesicle for release |
Zymogen granules | Things being converted into zymogen granules that are stored in the apical cytoplasm waiting for release signal. (Chyme from stomach) |
Enterokinase | In glycocalyx that can convert inacative trypsionogen to trysin which then converts all of the cells into active form so they can degrade the protein in the lumen of the gut |
Secretin | Secretin goes to interculated ducts release for copious of flow of alkaline juices that neutralizes acid of chyme |
CCK | Goes to gallbladder and causes contraction. Also goes to pancreas and acinar cells secrete enzymes in response |
Branches of Vagal nerve | Release acetylcholine in the vicinity of the acinar cells and they release enzymes in response |
What triggers exocytosis of zymogen granules? | Calcium. When CCK is there calcium rises and zymogen granules exocytos. IP3 can be release and cause release of stored calcium. |