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Chemical Immunity
Antibody-Mediated Immunity
Question | Answer |
---|---|
What is the definition of Antibody-Mediated Immunity? | the production of specific Antibodies in response to invading microbes |
What is the 1st step in Antibody-Mediated Immunity? | ARRIVAL of microbes in Lymph Organ |
What is the 2nd step in Antibody-Mediated Immunity? | BINDING of Microbial Antigen to receptors on specific B-cells |
What is the 3rd step in Antibody-Mediated Immunity? | MITOSIS of a specific B-cell population (clone), programed to produce Opposing Antibodies |
What is the 4th step in Antibody-Mediated Immunity? | "activated" B-cells are TRANSFORMED into Plasma or Memory cells |
What is the function of Plasma Cells? | SYNTHESIZE IgM Antibodies 1st, then IgG in 2nd response |
What is the function of Memory Cells? | remain dormant for years, then quickly divide and become Plasma cells during a 2nd response |
What is the significance of Memory cells? | save time/life in case of 2nd arrival of microbes |
Why do Microbes invade Lymph organs instead of Blood? | 1. Lower pressure; 2. Lymph organs are designed to pick up Microbes |
When is Antibody-Mediated Immunity activated? | after Non-specific Defense is breached |
How long does it take for Antibodies to be produced during a 1st exposure? | about 28 days |
How long does it take for Antibodies to be produced during a 2nd exposure? | about 7 days |
What is the 5th step in Antibody-Mediated Immunity? | Antibodies ATTACH to foreign cells Antigens and "mark" the cells for Phagocytosis by NK-cells or Macrophages |