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NMJ potential
put in order the seq of events for a action potential to happen at the NMJ
generation of the end plate | order in which it happens |
---|---|
an AP at the axon terminal opens voltage-gated calcium channels in the terminal button, calcium ions diffuse into the terminal button from the ECF | 1 |
acetylocholine is released by exocytosis from the vesicles in the terminal button | 2 |
ACh diffuses through the space b/w the nerve cell and muscle cell | 3 |
ACh binds to receptor sites on the motor end plate of the muscle cell | 4 |
this binding opens channels for sodium influx into the ICF of the muscle cell | 5 |
a local current flow that opens adjacent sodium channels in the motor end plate | 6 |
an action potential is initiated through the muscle fiber | 7 |
AChe acetylocholinesterase terminates the activity of ACh and NMJ | 8 |