Heme- Word Scramble

Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

Normal Size Small Size show me how

Heme-

AML,

Question	Answer
M0	Myeloblast without cell differentiation
M1	Myeloblast with minimal differentiation, some pros present; auer rods
M2	Myeloblast with maturation, auer rods
M3	Promyelocyte, blasts and myelocytes present, auer rods common, high incidence of DIC; t( 15; 17)
M4	Myeloblast and Monoblast; peroxidase/Sudan Black positive, specific esterase positive, non-specific esterase positive
M5	Monoblast
M6	Erythrocytic series
M7	Mekakaryocyte, CD42, CD61
RA	Refractory anemia with <5% blasts
RARS	Refractory anemia with sideroblasts and <5% blasts with ring sideroblasts
RAEB	Refractory anemia with excess blasts, 5-20% blasts
RAEBIT	Refractory anemia with excess blasts in transformation, 20-30% blasts
Hodgkin Lymphoma	Reed sternberg cells, bi-modal incidence, predictable( step-wise)
Non-Hodgkin Lymphoma	no reed sternberg cells, No pattern, unpredicatable spreading
ALL-L1	small lymphoblasts
ALL-L2	large and small lymphoblasts
ALL-L3	large lymphoblasts with vacuoles, Burkitt lymphoma
CLL	mature lymphocytes, smudge cells
Gaucher's Disease	Glucocerebroside accumulation
Niemann-Pick	Sphingomyelin accumulation; sea-blue histiocytes
Tay-Sachs	Sphingolipids, GM2 Ganglioside accumulation
Hurler, Hunter	Mucopolysaccharie accumulation
CGD	X-linked, ineffective killing of bacteria
Alder-Reilly	Large azurophilic granules, increased mucopolysaccharides (Hurler,Hunter)
Chediak-Higashi	large lysosomes, fusion of primary granules, seen in Albinism
May-Hegglin	large platelets, decreased # of platelets, Dohle bodies in segs, monos and lymphs
Pelger-Huet	Hyposegmented polys
Hgb A	2 alpha, 2 beta; 10-40% in newborn, 97% in adult
Hgb A2	2 alpha, 2 delta; <2% in newborn, 2% in adult
Hgb F	2 alpha, 2 gamma; 60-90% in newborns, 1% in adult
Howell-Jolly Body	DNA, wright stain, indicates HA, megaloblastic anemia, post-splenectomy
Basophilic stippling	RNA, wright and new-methylene blue stain, seen in thalassmeia and lead poisoning
Pappenheimer bodies	Siderotic granules, Iron, Wright and Prussian blue, seen in sideroblastic anemia, hemogolobinopathies
Heinz Bodies	Denatured precipitated hemoglobin, supravital stain, G6PD deficiency, thalassemia
Cabot rings	remnants of mitotic spindle, wright stain, megaloblastic anemia
pH 8.6 electrophoresis	A2, S, F, A (A2, C, E, Oarab, Charlem) (S, D, G, L)
pH 6.2 electrophoresis	F, A, Origin, S, C
% retics	# retics in 1000 rbc's/ 10
Absolute Retic	# RBCs x % retics
CRC	% retics x patients Hct/ 45
RPI	CRC/ mat time(usually 2) >2= adequate BM response
Beta Thalassemia Minor	microcytic, hypochromic; >90% A, 3.5-7% A2, F may be slightly increased
Beta Thalassemia Major	microcytic, hypochromic; little or no A, up to 98% F
Sickle Cell Anemia (SS)	>80% S, 1-20% F, 2-4.5% A2, no A
Sickle Cell Trait (AS)	50-65% A, 35-45% S, normal F, normal to slightly increased A2

Created by: mnuesmeyer on 2010-04-13