Psychosis 411 Word Scramble
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Question | Answer |
Disorders/conditions which may present symptoms of psychosis | bipolar, depression, other: med induced, illicit substance-induced, precipitated by med conditions |
Added to a pts normal presentation | Positive Symptoms |
Positive Symptoms Examples | hallucinations/illusions, delusions, disorganized speech, grossly disorganized or catatonic behavior, paranoia/suspiciousness |
Taken away from pts normal presentation | Negative Symptoms |
Negative Symptoms Examples | Asociality, anhedonia, affective impairment, alogia, poverty of speech, amotivation |
Cognitive Symptoms Examples | poor concentration, memory disturbances, inability to plan, difficulty executing tasks, poor abstractation, impaired decision making |
Typical Antipsychotics-Therapeutic benefit-receptor effects | Dopamine blockade |
Atypical antipsychotics-Therapeutic benefits-receptor effects | Dopamine and Serotonin blockade |
Dopamine blockade adverse events | worse neg symptoms, EPS & TD, polactin elevation |
Serotonin blockade adverse events | sedation, weight gain |
Typical Antipsychotics (1st gen) | Chlorpromazine, Thioridazine, Mesoridazine, Perphenazine, Trifluoperazine, Fluphenazine, Thiothixene, Haloperidol, Loxaopine, Molindone |
Atypical Antipsychotics (2nd gen) | Clozapine, Olanzapine, Risperidone, Quetiapine, Ziprasidone, Aripiprazole, Clozapine |
Sudden severe onset of abnormal posture (muscle movement). May involve tongue, jaw, eyes, neck, trunk, limbs, or toes. Usually 24-96 hrs after does | Dystonia |
Motor restlessness or inability to sit still. Pacing, shifting, shuffling, foot tapping, inner restlessness. | Akathisia |
Akinesia, bradykinesia, slowed speech, resting tremor, pill rolling tremor, cogwheel rigidity, postural abnormalities. Generally reversible | Pseudoparkinsonism |
Involuntary abnormal movements occurring late in onset in reaction to intiation of antipsychotic therapy. May include facial. tongue, limb, neck, or trunk movements. Early signs may be reversible, may become irreversible if undetected. | Tardive Dyskinesia (TD) |
Typical Antipsychotics Boxed Warning | QTc prolongation: Thioridazine, Mesoridazine |
Atypical Antipsychotics Black Box warning | increased rate of death in elderly w/ dementia |
Atypical Antipsychotics benefits | Less EPS, less TD, less hyperprolactinemia (except Risperidone), may be better at improving neg symptoms and cognition |
Atypical Antipsychotics Metabolic Complications | weight gain, hyperglycemia, cardiovascular probs, new onset diabetes, hyperlipidemia, hypercholesterolemia |
Clozapine (Atypical) | For treatment resistant pts. Unique potency for treatment of persistent psychotic symptoms, neg symptoms, and suididality. |
Clozapine ADR/contraindication | Agranulocytosis |
Chlorpromazine | Typical Antipsychotics (1st gen) |
Thioridazine | Typical Antipsychotics (1st gen) |
Mesoridazine | Typical Antipsychotics (1st gen) |
Perphenazine | Typical Antipsychotics (1st gen) |
Trifluoperazine | Typical Antipsychotics (1st gen) |
Fluphenazine | Typical Antipsychotics (1st gen) |
Thiothixene | Typical Antipsychotics (1st gen) |
Haloperidol | Typical Antipsychotics (1st gen) |
Loxaopine | Typical Antipsychotics (1st gen) |
Molindone | Typical Antipsychotics (1st gen) |
Clozapine | Atypical Antipsychotics (2nd gen) |
Olanzapine | Atypical Antipsychotics (2nd gen) |
Risperidone | Atypical Antipsychotics (2nd gen) |
Quetiapine | Atypical Antipsychotics (2nd gen) |
Ziprasidone | Atypical Antipsychotics (2nd gen) |
Aripiprazole | Atypical Antipsychotics (2nd gen) |
Clozapine | Atypical Antipsychotics (2nd gen) |
Created by:
lbreimeir
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