Antimicrobial Word Scramble
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| Question | Answer |
| What are the aerosolized antiinfectives we have learned about? | Pentamidine-Nebupent, Ribavirin-Virazole, Tobramycin-TOBI, Zanamivir-Relenza |
| What is the recommended dosage for Pentamidine/NebuPent? | 300mg/6ml sterile water; once/4wks |
| What is the recommended dosage for Ribavirin/Virazole? | 20mg/ml; 12-18hrs/day for 3-7days by SPAG |
| What is the recommended dosage for Tobramycin?TOBI? | 300mg bid; 28 days on/28 days off; >6yrs |
| What is the recommended dosage for Zanamivir/Relenza? | 10mg bid with DPI diskhaler; bid 5 days |
| What are the indications for Pentamidine/NebuPent? | PCP prophylaxis in HIV pt |
| What are the indications for Ribavirin/Virazole? | RSV |
| What are the indications for Tobramycin/TOBI? | P. aeruginosa in CF |
| What are the indications for Zanamivir/Relenza? | Influenza |
| What is the mode of action for Ribavirin/Virazole? | Inhibits DNA replication/reproduction |
| What special precautions should be taken when delivering Ribavirin/Virazole? | PPE's should always be worn; Women who are pregnant or planning pregnancy should not administer |
| What special precautions should be taken when administering Pentamidine/NebuPent? | Use Respigard II neb system, administer in negative pressure room or under exhaust, always wear PPEs |
| What is the mode of action for Pentamidine/Virazole? | Inhibits DNA, RNA, phospholipids and protein synthesis |
| What is the mode of action for Ribavirin/Virazole? | Stops viral DNA replication |
| What is the mode of action for Tobramycin/TOBI? | Bacterialcidal - blocks protein synthesis |
| What is the mode of action for Zanamivir/Relenza? | Binds to viral enzyme and block action |
| What are the side effects of Tobramycin/TOBI and Gentamicin? | Dizziness, nausea, neuromuscular blockade; |
| What can worsen the side effects of TOBI and Gentamicin? | Myasthenia and use of neuromuscular blockades |
Created by:
kreblackwell
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