WVSOM GI Word Scramble

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WVSOM GI

WVSOM GI Absorbtion of proteins, carbs, and fats

Question	Answer
Proteins are broken down to what before they are absorbed	amino acids
Surcose is broken down to what before it is absorbed	glucose and fructose
What else besides bring enzymes into contact with the food, does mixing accomplish	brings food in contact with brush border
What are fats broken down into	Free FA's and 2-monoglyceride
Most absorbtion takes place where?	duodenum
Where is B12 absorbed	ilium
where does digestion begin	mouth via salivary amylase
what types of bond does amylase break	1,4 glycosidic
what pH does amylase work best at	7
Amylase is secreted in what form. Active or inactive	active
Glucoamylase (maltase) does what	removes glucose monomers for transport from maltotriose or maltose
What are the products of amylase digestion	maltose, maltotriose, and a-limit dextrin
SGLT1 does what	acts as a co-transporter for glucose/galactose and Na+
GLUT5 is a channel for what monomer	fructose
GLUT2 does what	moves all monomers into the interstital space from the epithelial cells
What is the absorbtion of monomers driven by	The gradient created by basolaeral tranport
Poor nutrient absorbtion can be caused by what	maldigestion OR malabsorbtion (or both)
Meals high in sugar tend to have early or delayed gastric emptying	delayed
What is the rate limiting step of absorbtion	Uptake, not hydolysis
Regulators of intestinal phase	CCK, Vagus, and Secretin
Name three endopeptidases	Trypsin, chymotrypsin, Elastase
Name two carboxypeptidases	Carboxypeptidase A and B
Enterokinase is relased from the brushborder by what	bile salts
Trypsin acts as an inhibitor and	activator
What is the precusor to Trypsin	Trypsinogen
What is the precursor to chymotrypsin	chymotrypsinogen
Is the release of pancreatic proteases sufficent to to prepare all proteins for absorbtion	NO!
Are pancreatic proteases secreted in an active or inactive form	inactive
What activates pancreatic protease precursors	trypsinogen activaition by enterokinase
What must happen to olgiopeptides for them to cross the basolateral border	Cleavage into single aminoacids
Olgiopeptides are co-tranported with what to cross into the epithelium	H+
Amino acids are co-tranported with what to cross into the epithelium	Na+
Are larger or smaller peptides absorbed faster	larger
Too much build up of cholesterol and/or billirubin can cause the formation of what	stones
Is the reabsorbtion of NaCl and bicarb in the gallbladder isotonic, hypertonic or hypotonic	isotonic
What are the five processes in lipid assimilation	1. Secretion of Bile and various lipases2. Emuslification3. Ezymatic hydrolysis of ester bonds4. Solubilization of lipolytic products within bile salts micelles5. Transportation into and out of the enterocyte
What is emulsification	suspension of fat droplets
What does emulsification do	increases surface area of lipids
Which two lipases are acid tolerable	lingual lipase and food lipases
Does CCK inhibit or activate gastric emptying	inhibits
ACh causes a _______ of the gallbladder	release
Fat stimulates the release of ______	CCK
Acid stimulates the release of ________	secretin
Acinar cells release ________	enzymes
Ductal and centroacinar cells release_______	H20 and Bicarb
Problems with lipid digestion can be associated with which vitamins	A, E and D
What are the endogenous lipids	Cholesterol, phospholipids, and desquamated intestinal villus epithelial cells
What are the exogenous lipids	Triglycerides (90%), cholesterol, phospholipids
What are fatty acids and other lipid degredation products eventually converted into	triglycerides
Where do fat droplets form in the cell	smooth ER
Apoproteins are made in the ________ and then trnasported to the sER to associate with ________	rER, lipids
In what cell organelle are colymicrons and VLDL's made	Golgi (does glycosalation)
What molecules pass through the enterocyte and go directly to the blood	glycerol along with short and medium chain fatty acids
Most fat absorbtion is done in which part of the small intestine	Duodenum
Whipples disease is....	Inability to get colymicrons to the lympthatics

Created by: lowryc on 2008-11-20