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Epinephrine at Work Word Scramble

 
 

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Question Answer
STEP 1Binding of epinephrine/norepinephrine changes shape of beta receptor -> activates G-Protein
STEP 2G-Protein subunit activates adenylate cyclase
STEP 3Adenylate cyclase catalyzes conversion of ATP to cAMP
STEP 4cAMP activates protein kinase A
STEP 5Protein kinase phosphorylates Calcium channels, influx on calcium in cell, stimulates contraction
STEP 6protein kinase also phosphorylates calcium channels on sarcoplasmic reticulum. calcium then moves into the cytoplasm and stimulates contraction.
STEP 7Protein kinase phosphorylates myosin, stimulates contraction
STEP 8Protein kinase phosphorylates sarcoplasmic Calcium ATPase -> speeds removal of calcium from cytoplasm during relaxtion. decreases over relaxtion time.