Metabolic Bone Disease
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| A 4mo old child presents with non-bilious vomiting despite changing from milk-based formula to soy-based forumula. What is the most likely etiology? | Congenital pyloric stenosis
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| Which type of vasculitis fits the following descriptions?: infants and young children involved in coronary aa | kawasaki
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| Which type of vasculitis fits the following descriptions?: most common vasculitis | giant cell/temporal arteritis
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| Which type of vasculitis fits the following descriptions?: a/w hep B infxn | polyarteritis nodosa
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| Which type of vasculitis fits the following descriptions?: occlusion of ophthalmic a can lead to blindness | giant cell/temporal arteritis
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| Which type of vasculitis fits the following descriptions?: perforation of nasal septum | wegener's granulomatosis
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| Which type of vasculitis fits the following descriptions?: unilateral HA, jaw claudication | giant cell/temporal arteritis
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| What are the 4 mani causes of microcytic anemia? | Fe deficiency, Pb poisoning, thalassemias, and anemia of chronic dz
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| What should be seen in the joint aspirate of a pt with gouty arthritis? Pseudogout arthritis? | Gouty: Needle-shaped, Negatively birifringement crystals.
Pseudogout: rhomboid-shaped, Positively-birifringent crystals
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| What meds are used in the tx of acute gout? Of pseudogout? | Acute gout: NSAIDs, steroids, colchicine.
Pseudogout: NSAIDs, colchicine.
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| What are some of the endocrine causes of osteoporosis? | Hyperthyroidism, hyperparathyroidism, hypogonadism, Cushing's dz
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| What tx options are available to pts with osteoporosis? | Bisphosphonates, raloxifene, lifestyle mods (Ca, vit D supp), pulsatile PTH, stop steroids if possible
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| Serum Ca, Serum Phos, Alk Phos, PTH levels in Paget disease? | Norm Ca, norm phos, elev alk phos, norm PTH
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| Serum Ca, Serum Phos, Alk Phos, PTH levels in osteomalacia/rickets? | low ca, low phos, norm or elev alk phos, elev PTH
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| Serum Ca, Serum Phos, Alk Phos, PTH levels in chronic renal failure? | low ca, high phos, norm or elev alk phos, elev PTH
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| Serum Ca, Serum Phos, Alk Phos, PTH levels in osteoporosis? | all labs normal
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| Serum Ca, Serum Phos, Alk Phos, PTH levels in osteoporosis? | all labs normal
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| Serum Ca, Serum Phos, Alk Phos, PTH levels in primary hyperparathyroidism? | high ca, low phos, high alk phos, high PTH
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| Serum Ca, Serum Phos, Alk Phos, PTH levels in hypoparathryoidism? | low ca, high phos, norm alk phos, low PTH
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| Serum Ca, Serum Phos, Alk Phos, PTH levels in pseudohypoparathryoidism (tissue insensitivity to PTH)? | low ca, high phos, norm alk phos, high PTH
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| Which dz matches the following description?: knee x-ray reveals calcification of the meniscus | pseudogout
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| Which dz matches the following description?: needle-shaped, neg birefringent crystals | gout
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| Which dz matches the following description?: child with low-trauma fractures | osteogenesis imperfecta (OI)
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| Which dz matches the following description?: narrowing of the marrow cavity results in low H/H | osteopetrosis
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| Which dz matches the following description?: 55yo woman that trips and sustains a distal radius fracture | osteoporosis
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| A 6yo girl is brought to the peds ER for suspected broken bone in the forearm after falling while running around the backyard. This is her 3rd frac. Pt is non-responsive to questions b/c she is hard of hearing. What ophtho findings would you see? Tx? | Blue sclera (OI). Tx: activity restriction, surgical correction of deformities, bisphosphonates
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| A 60yo man is in clnic for a checkup. He is a new pt and you notice his legs are bowed out. He also is bent forward with kyphosis and is hard of hearing. He has no complaints besides his favorite hat feeling too small. Which imag test is most sens for dx? | Radionuclide bone scan. Dx is Paget dz.
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| Which fracture is a red flag for osetoporosis? | Colles fracture (distal radius +/- distal ulna)
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| What is teriparatide? | Pulsatile PTH subcut injection that builds bone
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| Obesity is protective against what bone disease? | Osteoporosis
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| What are the 2 long-term tx for gout? | probenecid and allopurinol
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| What drug should not be given during an acute gout attack? | Allopurinol
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| What physical exam finding rules out pseudogout? | Podagra (involvement of ig toe)
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| Which type of collagen is affected in OI? | Type I (oI)
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Created by:
sarah3148
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