kidney acid/base homeostasis
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| filtration of several substances that affect the ph of body fluids. Name them. | H+, Hco3, co2, H2Po4 and other fixed acids
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| Renal tubules selectively reabsorb and secrete these acids and bases to fine-tune the pH of the | plasma
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| route of filtration of acids/bases that the pH of body fluids takes in renal control of pH | from the glomerular capillaries into the glomerular capsule
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| When the amount of base increases in the body | If the plasma PH is too high, bicarbonate HCo_3 is filtered at the glomerulus but it is not reabsorbed. HCo-3 goes into the urine and is eliminated by the body
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| As HCO-3 (bicarbonate) is eliminated from the body, what happens to the pH of the plasma? | pH decreases, as more base is eliminated acid will increase and pH will decrease
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| When the acid in the body increases, | there are 3 major ways that the kidney tubules regulate the pH of body fluids activate
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| The three major ways that the kidney tubules regulate the pH of the body fluids | Reapsorption of HCo3, generating hco-3 by the kidney tubule cells, secretion of H+
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| Renal mechanisms for acid/base control are the | slowest, may take hours or days
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| Renal mechanisms for acid/base control allow for elimination of the ________ ________ from the body | fixed acids
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| Fixed acids are | Metabolic acids generated in the body that are elimated in the urine. Carbonic acid is not a fixed acid because it can be elimated via the lungs.
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| when does new bicarbonate become added to the plasma, when the pH increases and new buffering power is added to the plasma | when acid in the body increases
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| three major ways that the kidneys combat acidosis | Conserving (reabsorbing) of HCO3-, generating HCO3-, Secreting H+
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| The kidneys combat acidosis by conserving (reabsorbing) HCO3- in the _____ | PCT (proximal convoluted tubule)
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| The more co2 in the plasma as in the case of ______ ________ the faster it enters the cell | respirtory acidosis
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| Conserving (reabsorbing) HCO3- | CO2 arrives at the kidney tubule cell in the PCT from the filtrate, or plama, or from metabolic reactions within the cell.
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| With the PCT cell, co2 and h2o form | h2co3
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| the h2co3 splits into h+ and | and bicoarbonate
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| the H+ moves into the filtrate in exchange for Na+ thru a na+/H+ | antiport system
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| Antiport transport protein | A membrane-bound protein that will transport one substance in one direction in exchange for another specific substance moved in the other direction.
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