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Daniel's random 7

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
Leishmainia   hepatosplenomegaly, pancytopenia, spiking fevers  
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leishmeinia dx   macrophaegs containing amastigotes, peripheral blood smear  
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leishmeinia tx   sodium stibogluconate  
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which drug metabolizer into phenobital and phenylethylmalonamide?   primidone used for anticonvulsant  
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pneumo causes 40-65   Strep pneumo, H. influenzae, anaerobes, viruses, mycoplasma  
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S. pneumo >65   strep pneumo, influenza virus, anaerobes, H. influ,, gram negative rods  
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what do ATP ?   ATP - tRNA activation (charging) by aminoacyl tRNA synthetase  
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and GTP do in protein translation    
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I hyperchylomicronemia   chylomicrons, TG cholesterol increase, LPL deficiency or altered C2, presents with pancreatitis, HSM, eruptive/pruiritic anthomas; no increased risk for atherosclerosis  
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II familial hyperholesterolemia   LDL, cholesterol, AD, absent or decreased LDL receptor; accelerated atherosclerosis, tendon (achilles) xanthoma; corneal arcus  
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hypertriglyceridemia   VLDL, TG, hepatic VLDL overproduction; pancreatitis  
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abetalipoproteinemia   deficiency in B100 and B48  
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babesia and lyme's disease   ixodes tick  
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urease positive   proteus, ureaplasma, nocardia, cryptococcus, h. pylori, klebsiella  
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non linear DNA viruses   papilloma and polyoma (circular, supercoiled); hepadnaviruses - circular, incomplete  
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clonorchis sinensis   undercooked fish; inflammation of biliary tract -> pigment gallstones -> associates w/ cholangiocarcinoma; praziquentel  
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taenia solium (cestode, tapeworm) tx   praziquantel -> use bendazole for neurocysticercosis  
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leptospira interrogans   weil's dz -> severe jaundice and azotemia from liver and kidney dysfunction  
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M protein   group A strep; prevents phagocytosis  
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carcinoid tumor   sheets of uniform cells; minimal to no variation in shape and size of tumor cells; from enterochromaffin cells of intestinal mucosa  
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btonchioalveolar carcinoma   columnar cells that line the alveolar septa w/o vascular or stromal invasion; pneumonia like symptoms  
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B6 def   convulsions, hyperirritability, peripheral neuropathy (INH and OCP), sideroblastic anemia (decreased Hb, increased Fe)  
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B6 needed for synthesis of?   cystatione, heme, niacin, GABA  
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B6 function   transamination, decarboxylation, glycogen phosphorylase  
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hunter's   aggressive behavior; no corneal clouding  
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enzyme deficient in Hunter's   iduronate sulfatase  
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roseola HHV6   high fevers for several days -> may cause seizures; followed by diffuse macular rash  
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obligate anaerobe features   foul smell (short chain fatty acids), hard to culture, produce CO2 and H2 in tissue  
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giemsa   borellia, plasmodium, trypanosomes, chamydia  
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segmented viruses   BOAR bunyavirus (12), orthomyxovirus (8), arenavirus (2), reovirus (10-12)  
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yellow fever   monkey or human  
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yellow fever   black vomitis, jaundice  
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F fusion protein   paramyxovirus  
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silver stain   fungi, i.e. pneumocystis, legionella  
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onchocerca volvulus   ivermectin, river blindness, blackflies, black skin nodules, black sight  
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blood supply to proximal 1/3 ureter   renal artery  
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