Normal laboratory values & significance
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Hemoglobin Measures oxygen carrying capacity of blood N.R. = 12-18 g/100mL | Hemoglobin
Low:
>hemorrhage
>anemia
High:
>polycythemia
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Hematocrit Measures relative volume of cells and plasma in blood N.R.= 35%-50% | Hematocrit
Low:
>hemorrhage
>anemia
High:
>polycythemia
>dehydration
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Red Blood Cell Measures oxygen-carrying capacity of blood N.R.= 4-6 million/mm3 | Red Blood Cell
Low:
>hemorrhage
>anemia
High:
>polycythemia
>heart disease
>pulmonary disease
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White Blood Cell Measures host defense against inflammatory agents Infant N.R.= 8,000-15,000/mm3 4-7 yrs. old N.R.= 6,000-15,000/mm3 8-18 yrs. old N.R.= 4,500-13,500/mm3 | White Blood Cell
Low:
>aplastic anemia
>drug toxicity
>specific infections
High:
>inflammation
>trauma toxicity
>leukemia
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Neutrophils White blood cells that fight bacterial infection. N.R.= 54%-62% | Neutrophils will increase in
>bacterial infections
>hemorrhage
>diabetic acidosis
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Lymphocytes Large granular are more commonly known as the natural killer cells. Small ones are the T cells and B cells. N.R.= 25%-30% | >Viral and bacterial infection
>acute & chronic lymphocytic leukemia
>antigen reaction
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Eosinophils A WBC found in vertebrate blood, containing cytoplasmic granules that are easily stained by eosin or other acid dyes. N.R.= 1%-3% | Eosinophils will increase in
>parasitic & allergic conditions
>blood dyscrasias
>pernicious anemia
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Basophils A cell, especially a white blood cell, having granules that stain readily with basic dyes. N.R.= 1% | Basophils will increase in
>types of blood dyscrasias
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Monocytes A large, circulating, phagocytic WBC, having a single well-defined nucleus and very fine granulation in the cytoplasm. They constitute from 3 to 8 percent of the white blood cells in humans. N.R.= 0 - 9% | Monocytes is linked to
>Hodgkin’s disease
>lipid storage disease
>recovery from severe infections
>monocytic leukemia
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Prothrombin Time Measures extrinsic clotting factors N.R.= 11-16 sec | Prothrombin Time will be
>prolonged in liver disease
>impaired Vitamin K production
>surgical trauma with blood loss
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Partial Thromboplastin Time Measures intrinsic clotting of blood, congenital clotting disorders N.R.= 60-70 seconds | Partial Thromboplstin time is
>prolonged in hemophilia A,B, & C,
>Von Willebrand’s disease
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Platelets Measures clotting potential N.R.= 140,000-340,000/mL | Platelets is
increased in
>polycythemia
>leukemia
>severe hemorrhage
decreased in
>thrombocytopenia purpura
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Bleeding Time Measures quality of platelets N.R.= 1-6 min | Bleeding time will be
>prolonged in thrombocytopenia
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International Normalized Ratio (INR) Measures extrinsic clotting function N.R. Without anticoagulant therapy : 1 Anticoagulant therapy target range: 2-3 | Internation Normalized Ratio will be
>increased with anticoagulant therapy
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Urinalysis - Volume N.R. = 1,000-2,000 mL/d | Urinalysis will be
>increased in diabetes mellitus
>chronic nephritis
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Urinalysis - Specific gravity Measures the degree of tubular reabsorption and dehydration N.R. = 1.015-1.025 | U/A specific gravity will be
Increased in
>diabetes mellitus
Decreased in
>acute nephritis
>diabetes insipidus
>aldosteronism
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Urinalysis - pH Reflects acidosis and alkalosis N.R. = 6-8 | U/A pH
Acidic in
>diabetes
>acidosis
>prolonged fever
Alkalinic in
>urinary tract infection
>alkalosis
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Urinalysis - Casts N.R. = 1-2 per high power field | U/A Casts will yield
>renal tubule degeneration occuring in cardiac failure,pregnancy,hemoglobinuric-nephrosis
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Electrolytes - Sodium (Na) Reflects acid-base balance N.R. = 135-145 mEq | Electrolytes - Sodium (Na) will be
>increased in Cushing’s syndrome
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Electrolytes - Potassium (K) N.R. = 3.5-5 mEq | Electrolytes - Potassium (K) will be
>increased in tissue breakdown
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Electrolytes - Bicarbonate (HCO3) Ingestion of bicarbonate is a common remedy for ‘indigestion’, because it neutralizes stomach acid. N.R. = 24-30 mEq | (blank)
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Electrolytes - Chloride (Cl) N.R. = 100-106 mEq | Electrolyte - Chloride (Cl) will be
>increased in renal disease
>hypertension
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