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Final Review

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Question
Answer
Two important factors Darwin was unable to explain w/o understanding of heredity   He did not know the source of variation central to his theory. He could not explain how traits were passed from one generation to the next.  
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Population   a collection of individuals of the same species in a given area  
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Gene pool   the combined genetic information of all members of a particular population. contains more than one allele for each inheritable trait.  
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Sources of genetic variation   mutations, gene shuffling  
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Mutation   any change in a sequence of DNA. They can be limited to a single DNA base, affect lengthy segments of a chromosome, affect an organism's phenotype and fitness.  
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Why do mutations occur?   Because of mistakes in the replication of DNA or from radiation or chemicals in the environment.  
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Gene shuffling   creates most inheritable difference. Due to chromosomes moving independently and crossing over.  
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Sexual reproduction   major source of variation, can produce many different phenotypes, can produce many different genetic combinations. However, it cannot change the relative frequency of alleles in populations - it just shuffles them up.  
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# of phenotypes for a trait depends on   how many genes control the trait.  
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Most traits are controlled by   multiple genes  
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Natural selection on single gene traits   can change allele frequencies  
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If a trait made an organism less likely to survive, it might...   disappear from the gene pool.  
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If a trait had no effect on an organism's fitness, then...   it would not be under pressure from natural selection, so its frequency would remain unchanged.  
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Natural selection can affect the distributions of phenotypes 3 ways   directional selection, stabilizing selection, disruptive selection  
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Directional selection   individuals at one end have higher fitness than those in the middle or the other end. graph shifts  
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Stabilizing selection   Individuals near the center of the curve have higher fintness than individuals at either end. Gets skinnier.  
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Disruptive selection   individuals at the upper and lower ends of the curve have higher fitness than individuals near the middle. Graph bends or splits in middle.  
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Genetic drift   random change in allele frequencies in small populations  
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Founder effect   situation in which allele frequencies change as a result of the migration of a small subgroup of a population  
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Hardy-Weinberg principle   Allele frequencies in populations will stay the same unless something makes them change.  
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Genetic equilibrium   situation in which allele frequencies remain constant  
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5 conditions reuired to maintain genetic equilibrium   random mating, large population, no movement in/out, no mutations, no natural selection  
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