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Review of Test 3 -KIDNEY and LUNG stuff

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Question
Answer
LUNG I   LUNG I  
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By what method does O2 exchange occur?   Diffusion  
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Steps involved in breathing:   1. Ventilation 2. Exchange of O2 and CO2 b/w alveolar air and blood 3. Transport through heart circulation by bulk flow 4. Exchange O2 and CO2 in tissues 5. Cells use O2-->make CO2  
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Inspiration occurs by?   Increase volume in thoracic cage, thereby decreasing intrapleural pressure, increasing transpulmonary pressure, and expands thelungs and allows air in  
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Umm...summarize the above: (See p. 246, slide 3)   To inspire: Expand thorax, Pip < patm, Increase Transpulmonary pressure, expand lung, Palv <patm = air flow IN  
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What is transpulmonary prssure?   (Palv - Pip)  
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How does FORCED expiration work (P. 248)   1. Decrease thorax 2. Return pressures of Pip, Ptranspulm, and recoil lungs-->Patm < Palv = air flow out  
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How does air flow??   From area with greater pressure to area with less pressure  
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LUNG II   LUNG II  
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What does the respiratory quotient measure?   How much cell uses O2 and produces CO2  
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What is hypoventilation? C and O amounts? What does this lead to?   Shallow breathing; high C, low O; not enough oxygenated blood  
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So what do you do??   You breath  
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What happens to CO2 if you decrease PO2 in venous side? Arterial side?   Venous: Increase CO2, Arterial, Decrease CO2  
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As systemic venous blood flows through the pulmonary capillaries, what happens to O and CO2?   There's diffusion of Oxygen from alveoli to blood and of carbon dioxide from blood to alveoli  
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Rank the following in order of how saturated with Oxygen (from lowest to highest): High elevation, excercise, normal   Excercise, high elevation, to normal  
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What is the common form in which you would find circulating CO2?   bicarbonate  
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What happens to the bound hydrogen ions when the blood flows through the lung capillaries?   They are released and combine with bicarbonate to ---:>CO2 and Water  
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LUNG III (LAST)   LUNG III (LAST)  
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What is the curoff signal for breathing?   Pulmonary stretch receptors  
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What neural strucutre controls breathing?   Medulla  
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What are the two inputs to the medulla that control breathing?   Peripheral and central chemoreceptors  
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What are peripheral chemoreceptors MOST sensitive to a change to? What are they sensitive to changes of overall?   Most: CO2; also PO2 and H+  
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Central chemoreceptors respond to changes in? [H+] [PCO2] or [PO2]?   [H+}; associated with an increase in PCO2  
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Generally, what MUST we lower the levels of in our blood? What do we automatically respond to even if their levels go up a bit?   PCO2 and [H+]; often, an increase in PCO2-->increases H+  
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Ventiallation during excercise:   Ventiallation during excercise: BELOW  
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What happens to [H+] [PCO2] and PO2 during moderate excercise:   Unchanged  
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Which one increases in STRENOUS excercise?   [H+] increases in strenuous excercise b/c of lactic acid fermentation  
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KIDNEY I   KIDNEY I: STRUCTURE AND FUNCTION  
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What are teh three processes of the kidney?   1. Glomelular filtration 2. Tubular Secretion 3. Tubular Reabsorption (resorption)  
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Excretion =   (filtered - secreted) / resorped  
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***What drives glomelular filtration?   Hydrostatic pressure in glomerular capillaries  
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***What opposes glomerular filtratio?   Hydrostatic pressure in BOWMAN"S capsule and osmotic force (due to proteins..etc.)  
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GFR is?   Fluid filtered from the glomeruli into Bowman's space  
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What does tubular reabsoprtion aim to do?   Get good stuff out of urine...like glucose  
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What is the predominant method for reabsoprtion in kidney?   BY DIFFUSION via wate concetnration gradients  
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Tubular secretion involves?   Moving substances from peritubular capillaires to tubules.  
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RECALL:What are the two pathways of getting something into the tubule?   Glomerular filtration and tubular secretion  
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What goes through this?   K+, H+  
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Clearence of a substance =   mass of S excreted per unit time/Plasma concentration of S  
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How does urination work by REFLEX (micturition)   1. Distend bladder 2. Increase parasympathetic to bladder muscle 3. Inhibit motor neurons to external urethral sphincter  
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How does urination work by VOLUNTARY CONTROL (micturition)   1. Distend 2. Parasymp input to BOTH bladder muscles and motor nerves of external urethral sphincter  
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KIDNEY II   KIDNEY II  
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I'm   (blank)  
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Going   (blank)  
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To   (blank)  
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Give up   (blank)  
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on those   (blank)  
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Points   since there's too much info to re-memorize  
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KIDNEY III   KIDNEY III (LAST!!!)  
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Osteoblasts:   Lay down bone  
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Osteoclsts:   Break down bone  
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Osteocytes:   What osteoblasts become after they've layed down bone  
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Osteoblasts do what to plasma Calcium levels?   DECREASE it since they use it to make bone  
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Osteoblasts do what to calcium levels?   INCREASE since they btreak down bone and release the calcium in them  
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What hormones FAVOR bone formation?   D3  
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What hormones favor bone BREAKDOWN (resportption)?   PTH (parathyroid)  
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Kidney regulation of calcium resporption is under what control?   hormonal control  
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What does vitamin D3 do??   Makes the GI absorp more Calcium injested in bood  
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