Bakhtar-Female Reproductive Pathology
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| types of Paget's Disease | intraepithelial adenocarcinoma
bone: xs bone resorption as result of inflammatory response
breast: malignant condition with skin changes involving nipple
extramammary: involves primarily epidermis but occasionally extends into underlying epidermi
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| endometriosis | can occur anywhere in the body
deposition of 2 outta 3:
1)endometrial glands
2)endometrial stroma
3)hemosiderin
major cause of infertility and pelvic pain
origin: regurgitation thru FT, dissem. thru veins/lymphatics, metaplasia from coelomic e
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| low grade squamous intraepithelial lesions LGIL, LGSIL | CIN I-moderate dysplasia
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| high grade squamous intraepithelial lesions | CIN II-moderate dysplasia
CIN III-severe dysplasia
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| tamoxifen | used as anti-estrogen therapy for hormone-receptor positive breast cancer in pre-menopausal women
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| salpingitis | infxn and inflamm of FT
2 types:
1)acute
2)chronic=change in architecture
TB play big role in salpingitis worldwide; PID in U.S.
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| salpingitis isthmica nosdosum | diverticulosis of FT: thickening of tunica musclaris of isthmic portion leads to complete obliteration of tubal lumen
usually bilateral
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| Stein-Leventhal syndrome | polycystic ovarian syndrome
follicular cysts, anovulation, obesity, hirsutism
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| benign germ cell tumor | mature teratoma
ectodermally derived
frequently skin, respiratory, conjunctiva epithelium
any component of teratoma can develop a "mature malignancy"
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| malignant germ cell tumors | dysgerminoma
embryonal
immature teratoma
yolk sac
choriocarcinoma
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| dysgerminoma | malignant germ cell tumor
undifferentiated
ovarian counterpart of seminoma
large vesicles with clear cytoplasm
prominent lymphoid component
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| embroynal tumor | malignant germ cell tumor
primitive
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| immature teratoma | malignant germ cell tumor
somatic: resembles differentiation seen in fetus or embryo
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| yolk sac tumor | malignant germ cell tumor
extraembryonic
rich in AFP
Schiller Duval Body
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| choriocarcinoma | malignant germ cell tumor
placental or ovarian origin
cytotrophoblasts and syncytiotrophoblasts present
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| surface epithelial tumors | 1)serous
2)mucinous
3)pseudomyxoma peritonei
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| tumor metastasis to ovaries | most common origin from gyn system
2nd common origin from digestive tract
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| Krukenburg tumor | malignancy in ovaries that metastasized from stomach cancer
found 80% in both ovaries
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Created by:
kphom001
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