Nervous System Diseases
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| NEISSERIA MENINGITIDES | NEISSERIA MENINGITIDES
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| ID it: | Gram negative diplococci
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| What virulence factor does it have and of what serological groups? | Capsule of group A, B, C
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| What disease does it cause? and at what age? | Meningitis; for those <2 yr
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| What conditions are associated with Nisearia meningitides? | Meningococcemia
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| What is meningococcemia? | septecemia that is rapidly fatal
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| EPIDEMIOLOGY | EPIDEMIOLOGY
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| Where would you find it? | Throat and nasopharynx
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| Is it spreadable? | Yes, quickly contain it
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| How would you diagnose and treat it (at what speed, too)? | Gram stain of CSF, culture and sero type it; TREAT QUICKLY with abs
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| How do we prevent it? What have we been able to prevent? Have we prevented all? | Use a vaccine to prevent it. We have vaccines for A, C, but not B
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| What is the ID of STREPTOCOCCUS PNEUMONIAE? | Gram positive Cocci in pairs
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| What is the ID of LISTERIA MONOCYTOGENES? | Gram positive ROD
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| BACTERIAL INFECTIONS WITH TOXEMIA | TOXEMIA
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| What are the characteristics (Gram, type of growth, virulence) of CLOSTRIDIUM TETANI? | Gram Positive obligate anaerobe, and is a spore former (tetanus toxin)
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| What DISEASES are associated with it: | Nenatal and adult tetanus
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| What does nenonatal tetanus involv? and how is it caused? | Umbilical stump infection b/c of contaminated equipment
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| What is ADULT tetanus AKA? | lock-jaw
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| What is the process of infectino and type of infection invovled in this cause (reverse orderwhen answering and end with what specifically causes you to die?) | Rusty nail infection formed. Steps are: 1. Release toxin 2. PNS cells 3. CNS 4. Spastic muscles-->respiratory failure
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| EPIDEMIOLOGY | EPIDEMIOLOGY
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| What condition is most common in poor countries? | Nenonatal
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| What is a toxoid? | Similar to toxin, but no sporagenic effects
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| How would you treat it? Which is most important? | Debridement (remove dead tissue), TIG (passive vaccine that only works a few times), and VACCINE
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| What sort of vaccinations are out there for it? | Tetanus toxoid and DTP vaccine
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| BACTERIAL INFECTIONS OF THE PNS | PNS INFECTIONS
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| What is toxemia due to? | Exotoxin
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| Why are conjugate vaccines good? | Stuck to small protein (exotoxin) and good AB response
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