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OSU-CHS virology

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Question
Answer
blocks protein processing + assembly, PI for HIV   Atazanavir Fosamprenavir Lopinavir Ritonavir  
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Foscarnet, PFA or PAA   Binds and inhibits herpesvirus DNA polymerase HSV, CMV  
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Immunoglobulin   Blocks attachment or penetration HAV, HBV, CMV, Rabies, RSV, Measles, VZV  
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Enfuvirtide (Fuzeon)   Blocks attachment or penetration, gp41 analog for HIV  
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Zinc gluconate, Zinc acetate   Blocks attachment or penetrartion, Binds to zinc finger domains in VAP for Cold viruses  
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Amantadine, Rimantadine   Blocks M2 ion channels, Inhibits dissassembly and penetration of Influenza A  
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Interferon alpha   Blocks transcription, protein synthesis HAV, HBV, HCV, HPV…  
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Pleconaril   Blocks uncoating, Binds to picornavirus capsid picornaviruses  
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Oseltamivir (Tamiflu), Zanamivir (Relenza)   Inhibits neuraminidase, Virus egress for Influenza A + B  
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Entecavir (Baraclude) Nucleoside analog, Lamivudine (3TC, Epivir)   Inhibits reverse transcriptase for HBV  
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Efavirenz   Non-nucleoside analog, Inhibits reverse transcriptase HIV  
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Telbivudine (Tyzeka)   Nucleoside analog, Causes DNA chain termination chronic HepB  
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Ganciclovir   Nucleoside analog, Causes DNA chain termination for CMV  
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Acyclovir   Nucleoside analog, Causes DNA chain termination for HSV, VZV  
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Zidovudine (AZT)   Nucleoside analog, Causes DNA chain termination for HIV  
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Ribovarin   Nucleoside biosynthesis, mRNA capping for RSV, HBV + other RNA viruses  
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Adefovir   Reverse transcriptase inhibitor for HBV  
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Tenofovir   NucleoTide analog, Causes DNA chain termination for HIV  
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