Drug Classes/Drugs/MOAs
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| Natural Penicillins | Penicillin G | Cell Wall Inhibitor, Beta-Lactam antibiotic
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| Natural Penicillins | Penicillin V | Cell Wall Inhibitor, Beta-Lactam antibiotic
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| Antistaph Penicillins | Methicillin | Cell Wall Inhibitor, Beta-Lactam antibiotic
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| Antistaph Penicillins | Nafcillin | Cell Wall Inhibitor, Beta-Lactam antibiotic
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| Amino Penicillins | Ampicillin | Cell Wall Inhibitor, Beta-Lactam antibiotic
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| Amino Penicillins | Amoxicillin | Cell Wall Inhibitor, Beta-Lactam antibiotic
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| Antipseudomonal Penicillins | Piperacillin | Cell Wall Inhibitor, Beta-Lactam antibiotic
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| Antipseudomonal Penicillins | Carbenicillin | Cell Wall Inhibitor, Beta-Lactam antibiotic
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| Antipseudomonal Penicillins | Ticarcillin | Cell Wall Inhibitor, Beta-Lactam antibiotic
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| Antipseudomonal Penicillins | Mezlocillin | Cell Wall Inhibitor, Beta-Lactam antibiotic
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| 1st Gen Ceph | cefazolin | Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
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| 1st Gen Ceph | Cephalexin | Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
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| 2nd Gen Ceph | Cefaclor | Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
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| 2nd Gen Ceph | Cefoxitin | Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
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| 2nd Gen Ceph | Cefuroxime | Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
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| 2nd Gen Ceph | Cefamandole | Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
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| 3rd Gen Ceph | Cefoperazone | Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
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| 3rd Gen Ceph | Cefotaxime | Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
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| 3rd Gen Ceph | Ceftazidime | Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
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| 3rd Gen Geph | Ceftriaxone | Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
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| 4th Gen Ceph | Cefepime | Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
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| Carbapenems | Imipenem | Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
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| Carbapenems | Meropenem | Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
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| Carbapenems | Ertapenem | Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
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| Monobactams | Aztreonam | Bactericidal; Inactivate PBPs, Prevent crosslinkage formation; Allow autolysins to proceed
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| Other: Affecting Cell Wall | Vancomycin | Glycopeptide inhibits cell wall synthesis by preventing peptidoglycan elongation; bactericidal; bacteriostatic for enterococci
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| Other: Affecting Cell Wall | Teicoplanin | (blank)
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| Other: Affecting Cell Wall | Bacitracin | (blank)
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| Other: Affecting Cell Wall | Polymyxin | (blank)
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| Tetracyclines | Tetracycline | Bacteriostatic; Blocks protein synthesis by binding to 30S ribosomal subunit & blocking access of amino acyl-tRNA to mRNA ribosome complex at acceptor site. Prevents addition of amino acids to growing peptide.
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| Tetracyclines | Doxycycline | Bacteriostatic; Blocks protein synthesis by binding to 30S ribosomal subunit & blocking access of amino acyl-tRNA to mRNA ribosome complex at acceptor site. Prevents addition of amino acids to growing peptide.
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| Aminoglycosides | Gentamicin (prototype) | Bactericidal; Entry of drugs into bacterial cells; Blocks Protein synthesis at 30S
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| Aminoglycosides | Amikacin | Bactericidal; Entry of drugs into bacterial cells; Blocks Protein synthesis at 30S
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| Aminoglycosides | Streptomycin | Bactericidal; Entry of drugs into bacterial cells; Blocks Protein synthesis at 30S
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| Macrolides | Erythromycin | Bacteriostatic; Blocks protein synthesis at 50S inhibiting aminoacyl translocation rxn
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| Macrolides | Clarithromycin | Bacteriostatic; Blocks protein synthesis at 50S inhibiting aminoacyl translocation rxn
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| Macrolides | Azithromycin | Bacteriostatic; Blocks protein synthesis at 50S inhibiting aminoacyl translocation rxn
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| Other Protein Synthesis Inhibitors | Chloramphenicol | Binds to 50S and inhibits peptidyl transferase step of protein synthesis
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| Other Protein Synthesis Inhibitors | Clindamycin | Binds to 50S and inhibits peptidyl transferase step of protein synthesis
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| Other Protein Synthesis Inhibitors | Streptogramins (quinupristin & dalfopristin) | Bacteriostatic; blocks protein synthesis at 50S inhibiting aminoacyl translocation rxn
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| Other Protein Synthesis Inhibitors | Linezolid | Bacteriostatic; blocks protein synthesis at 50S inhibiting aminoacyl translocation rxn
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| Other Protein Synthesis Inhibitors | Telithromycin | Bacteriostatic; blocks protein synthesis at 50S inhibiting aminoacyl translocation rxn - binds 10x tighter
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| Other | Metronidazole | Metabolized to active form by ferredoxin that inhibits DNA
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| Other | Daptomycin | Binds to cell membrane causing rapid depolarization; loss of membrane potential inhibits protein, DNA & RNA synthesis
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| Sulfonamides | Sulfacetamide | Bacteriostatis; Competes with PABA for dihydropteroate synthase & prevents synthesis of folic acid
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| Sulfonamides | Silver Sulfadiazine | Bacteriostatis; Competes with PABA for dihydropteroate synthase & prevents synthesis of folic acid
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| Sulfonamides | Trimethoprim-Sulfamethoxazole | inhibits dihydrofolate reductase blocking purine, pyrimidine & amono acid synthesis - synergistic preventing of formation of tetrahydrofolic acid
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| Fluoroquinolones | Norfloxacin | Inhibition of topoisomerase II
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| Fluoroquinolones | Ciprofloxacin | Inhibition of topoisomerase II
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| Fluoroquinolones | Ofloxacin | Inhibition of topoisomerase II
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| Fluoroquinolones | Gatifloxacin | Inhibition of topoisomerase II
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| Fluoroquinolones | Levofloxacin | Inhibition of topoisomerase II
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| Fluoroquinolones | Moxifloxacin | Inhibition of topoisomerase II
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| Fluoroquinolones | Sparfloxacin | Inhibition of topoisomerase II
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| Urinary Tract Antiseptic | Nitrofurantoin | Metabolized to active form by the bacteria inhibiting various enzymes & damages DNA
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| Antigout Agent | Probenecid | Inhibits tubular reabsorption of uric acid increasing the urinary excretion of uric acid
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