blood gases;buffers
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pH | index of acidity or alkalinity of the blood
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blood gases | body's mechanism to maintain acid-base balance
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acidosis | metabolic state that leads to acidema
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alkalosis | metabolic state that leads to alkaemia
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normal pH | 7.35-7.45
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acid | substance that can yield a hydrogen ion or hydronium ion when dissolved in water
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base | substance that will yield a hydroxyl(OH-) ion when dissolved in water
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K value | relative strenth of acids and bases and their ability to dissociate in water
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buffer | combination of a weak acid or base and its salt so that it resists changes in pH.
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pCO2 | measurement of tension or pressue of carbon dioxide dissolve in blood
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pCO2 reference range | 35-45mmHg
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pO2 | meansurement of tension or pressure of oxygen dissolved in blood
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pO2 reference range | 80-110mmol/L
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decreased pO2 is seen in... | decreased pulmanary ventilation
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acid-base balance | maintenance of H+; increased H+, decreased pH; decreased H+, increased pH
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bicarbonate-carbonic acid | buffer in highest concentration in plasma
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Henderson-Hasselbalck equation | relates pH, HCO3, pCO2
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hemoglobin buffer | transports acid from tissues to lungs
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phosphate buffer | intracellular buffer
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albumin/other proteins | buffers system that binds H+ because of net negative charge
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respiratory acid-base disorder | caused by ventilatory dysfunction
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metabolic acid-base disorder | caused by renal dysfunction
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compensation | body's attempt to restore acid-base balance
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fully compensated | body pH has returned to normal range
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partially compensated | body pH is approaching normal range
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metabolic acidosis | decrease pH and decreased HCO3-
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metabolic alkalosis | increase pH and increased HCO3-
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respiratory acidosis | decrease pH and increased CO2
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respiratory alkalosis | increase pH and decreased CO2
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anion gap | eastimate of unmeasured anions and cations
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