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Step III - Renal 1

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Question
Answer
Hyaline casts, urine osm >500, FeNa <1%, urine Na <20   Pre-renal  
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What are the causes of pre-renal azotemia   HYPO-volemia, HYPO-tn (<90), CHF, constrictive cardx, low onc pressure, renal aa stenosis  
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Causes of post-renal   Strictures, stones, CA bladder/prostate/cervix, neurogenic bladder  
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Muddy brown/granular casts   ATN  
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Hyaline casts   Pre-renal  
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What are the common causes of ATN   Toxic injury and HYPOperfusion  
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MCC toxin induced renal insufficiency   Aminoglycosides, amphotericin, chemo (cisplatin), IV contrast dye  
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What lab test can help in evalx ATN from contrast   Mg  
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Fever, Rash, Eosinophilia/uria, WBC casts. Exposure to drug or infection   AIN  
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What is the FeNa and urine Osm in AIN   FENa >2%, Dilute urine (Osm < 350)  
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h/o Abx (PCN, ceph, NSAIDs, phenytoin, diuretics, sulfa, quinolones) a/w what type intrarenal renal failure   AIN  
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h/o infection/autoimmune (SS, SLE, sarcoidosis) a/w what type intrarenal renal failure   AIN  
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What is the best initial test for AIN and what does it show   UA showing WBCs  
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Most accurate test for AIN   Wright stain OR Hansel’s stain of urine showing eosinophils  
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Tx for AIN   None; resolves on own  
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What drug causes hemorrhagic cystitis and NOT renal failure   Cyclophosphamide  
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What are some causes of rhabdo that lead to intrarenal failure   Seizures, crush injury, immobility in intoxicated pt, low K+ causing muscle necrosis, pt on statin  
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What is the best initial test for rhabdo induced intrarenal failure   UA showing large amounts RBCs but no cells  
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Most accurate test for rhabdo induced intrarenal failure   Urine myoglobin  
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Decreased bicarb, low Ca2+, incr K+ labs seen in what type of renal failure   rhabdo induced intrarenal failure  
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Tx for rhabdo induced intrarenal failure   Bolus nL saline, mannitol diuresis, alkalinization of urine  
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Pt in case has rhabdomyolysis. Most URGENT step in management and why   EKG; rhabdo causes HYPER-kalemia which is risk for arrthymia  
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Pt intoxicated from suicide attempt w/ antifreeze. What kind of renal failure   Crystal induced  
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What type of crystals are seen in ethylene glycol renal failure and what is the shape   Oxalate “envelope” crystals  
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What is the best initial test for crystal uropathy   UA  
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What is the best initial tx for crystal uropathy   Ethanol OR fomepazole w/ dialysis  
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What kind of crystals are seen in tumor lysis syndrome   Urate  
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Tx for urate crystal renal failure   Hydration and allopurinol  
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What can you give a pt that has DM/HTN who absolutely needs contrast dye   Hydrate w/ nL saline + bicarb/N-acetylcysteine  
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What are some kidney insults resulting from NSAIDs   ATN, AIN, nephrotic syndrome, afferent aa vasoconstrx  
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Red blood cells, red cell casts, proteinuria <2g in 24, edema   Glomerulonephritis  
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Most accurate test for glomerulonephrx   Kidney bx  
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