More info from Block 1
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
|
|
||||
|---|---|---|---|---|---|
| Diseases a/w Collagen deficits | scurvy (Vit C deficiency); Ehlers-Danlos syndrome; Osteogenesis Imperfecta
🗑
|
||||
| disease w/ elastin/fibrillin deficit | Marfan syncrome
🗑
|
||||
| vascular transmigration; facilitated by PECAM-1 | diapedesis
🗑
|
||||
| vascular dilation esp arterioles; increase vascular permeability esp venules | histamine
🗑
|
||||
| increase vascular permeability | serotonin
🗑
|
||||
| release arachidonic acid from lipid membrane of cells; release PAF from lipid membrane of cells | PLA2
🗑
|
||||
| indcues platelet agreggation; induce neutrophil oxidative burst; induce arachidonic acid production by activating PLA2; induces leukocyte-endothelial adhesion | Platelet Activating Factor (PAF)
🗑
|
||||
| secreted by NK cells; plays the predominant role in macrphage activation (esp in relation to granuloma formation) | interferon gamma (INF-y)
🗑
|
||||
| stimulate neutrophil adhesion | leukotrienes
🗑
|
||||
| exert an inhibitory effect on many inflammation processes | lipoxins
🗑
|
||||
| elevated ESR | RBCs clump because of the increase of acute phase proteins esp fibrinogen
🗑
|
||||
| occurs when injurious agent or forgein material cannot be eradicated & body switches to a strategy of containment | Chronic Suppurative inflammation
🗑
|
||||
| chronic macrophage activation causes macrophages to swell and take on an epitheloid cell appearance | Granulomatous inflammation
🗑
|
||||
| most common cause of MV stenosis? | Rheumatic heart disease
🗑
|
||||
| most common cause of MV regurgitation? | papillary dysfunctino due to ischemic heart dis or Mitral valve prolapse due to myxomatous degenration of the MV
🗑
|
||||
| most common cause of aortic valve stenosis? | congenital bicuspid aortic valve & senile fibrocalcific degeneration
🗑
|
||||
| most common cause of myocarditis? | Coxsackie B & Adenovirus type 2 & 3
🗑
|
||||
| mitral valve stenosis triad? | 1) loud S1; 2) mitral valve opening snap; 3) mid-distolic murmur best heard @ cardiac apcex
🗑
|
||||
| primary hypertrophic cardiomyopathy a/w mutations in the??? | myosin heavy beta chain; actin; tropomyosin; titin
🗑
|
||||
| where do we see WHORLED PATTERN in the myocardial muscle bundles? | Primary Hypertrophic Cardiomyopathy
🗑
|
||||
| pulmonary circulation maintained by Right Atrium | Fontan heart (seen in Arrhythmogenic RV Cardiomyopathy)
🗑
|
||||
| repalcemnt of portions of the myocardial wall, usually the RV by fibrofatty tissue w/ loss of cardiocytes; show interved T waves in anterior chest leads over R ventricle and epsilon wave in early ST segment; only effective Tx: defibrillator implantation | Arrythmogenic RV Cardiomyopathy
🗑
|
||||
| Where is S3, S4 & S7 present? | Congestive Heart Failure
🗑
|
||||
| difficulty in repolarization leads to uncoordinated repolarization which predisposes to episodes of spontaenous ventricular re-entry arrythmias sep Torsade de Pointes | Long QT syndrome
🗑
|
||||
| compensatory mechanism of cells incapable of cell division | hypertrophy
🗑
|
||||
| organs where fatty change (steatosis) is common? | liver, myocardiumk kidney
🗑
|
||||
| enzymatically binds to damaged proteins to facilitate their removal | ubiquitin
🗑
|
||||
| proteins involved in apoptosis also involved in tumoregenesis | bcl2 & p53
🗑
|
||||
| adult progeria; autosomal recessive; defective DNA helicase enzymes | Werner Syndrome
🗑
|
||||
| pediatric progeria | Cockayne syndrome
🗑
|
||||
| Connective tissue disorder; autosomal recessive | Acrogeria
🗑
|
||||
| help regulate the clotthing cascade | alpha-2-antiplasmin
🗑
|
||||
| inhibits the initiation of complement cascade | c1 esterase inhibitor
🗑
|
||||
| neutralize reactive oxygen radicals | Metal binding protein (manganese superoxide dismutase)
🗑
|
||||
| increased levels of bone marrow granulopoiesis; cytoplasmic areas of condensed ribosomes | Dohle bodies
🗑
|
||||
| valve most likely involved in IVDA related Infective endocarditis | Tricuspid valve
🗑
|
||||
| Infective Endocarditis where pahents have NO structural disease and NO preexisting heart murmur | community acquired ACUTE IE
🗑
|
||||
| s/s: intermittent claudication, impotence, decreased or absent femoral pulses; a/w aortic narrowing in the abdominal aorta below the renal stenosis | Leriche syndrome
🗑
|
||||
| fibrointimal proliferation creating 'onion skin' appearache; commonly located in kidnyes | hyperplastic arteriosclerosis
🗑
|
||||
| higher lipid content of lipid core; thinner fibrous cap; increased leukocyte activity at shoulder regions of plaque | vulnerable plaque
🗑
|
||||
| due to reoxygenation in reversible cardiocyte injury which causes extreme contraction of the cardiocyte filaments | contraction band necrosis 'rigor bands'
🗑
|
||||
| retina may demonstrate orange-yellow plaque at bifurcation of vessels | Hollenhurst plaque (seen in cholesterol embolization syndrome)
🗑
|
||||
| red-blue skin momttling in reticular (net-like) pattern over distal extremities due to blood flow stasis | cutaneous livedo reticularis
🗑
|
||||
| chronic hypoxia due to chronic respiratory insufficiency due to inhibition of respiratory movement from obesity | Pickwickian syndrome
🗑
|
Review the information in the table. When you are ready to quiz yourself you can hide individual columns or the entire table. Then you can click on the empty cells to reveal the answer. Try to recall what will be displayed before clicking the empty cell.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Created by:
cbelmonte
Popular Medical sets