Anesthesia definitions
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| Name the state or ability to perceive, to feel, or to be conscious | Awareness | Robins K et al. Intraoperative Awareness During General Anesthesia for Cesarean Delivery Anesth Analg, 109:886-890, 2009
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| Name a type of memory in which conscious recall of specific facts and events | Explicit | Robins K et al. Intraoperative Awareness During General Anesthesia for Cesarean Delivery Anesth Analg, 109:886-890, 2009
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| Name a type of memory in which previous experiences aid without conscious awareness of these previous experiences | Implicit | capable of being understood from something else though unexpressed; Latin implicitus involved, obscure, variant past participle of implicāre | Robins K et al. Intraoperative Awareness During General Anesthesia for Cesarean Delivery Anesth Analg, 109:886-890, 2009
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| Process whereby exposure to a stimulus influences response to a subsequent(later) stimulus | Priming | Priming is the implicit memory effect | Robins K et al. Intraoperative Awareness During General Anesthesia for Cesarean Delivery Anesth Analg, 109:886-890, 2009
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| State in which information from surroundings can be processed | Consciousness | Robins K et al. Intraoperative Awareness During General Anesthesia for Cesarean Delivery Anesth Analg, 109:886-890, 2009
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| Ability to retrieve stored memories | Recall | Robins K et al. Intraoperative Awareness During General Anesthesia for Cesarean Delivery Anesth Analg, 109:886-890, 2009
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| Absence of recall; a condition in which one's memory is lost | Amnesia | Event not retained in long-term memory | Robins K et al. Intraoperative Awareness During General Anesthesia for Cesarean Delivery Anesth Analg, 109:886-890, 2009
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| Pharmacogenetic disorder in which anesthetics trigger a sustained increase in intramyoplasmic Ca2+ that leads to hypermetabolism, muscle rigidity, rhabdomyolysis, and death | Malignant Hyperthermia | (MH) autosomal dominant inheritance | Nelson TE. Malignant hyperthermia: a pharmacogenetic disease of Ca++ regulating proteins. Curr Mol Med 2002;2:347–69
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| Specific treatment for MH | Dantrolene | Dantrolene sodium is the only drug effective for treatment of Malignant hyperthermia | Anesth
Analg 2010;111:1400 –10
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| The most common site of mutations in MH | Ryanodine receptor | (RYR1) for the skeletal muscle intracellular Ca2+ release channel. It is not yet feasible to screen the entire population for RYR1 mutations because more than 170 variants, of which 29 are known causative mutations | Robinson R, Carpenter D, Shaw MA, Halsall J, Hopkins P. Mutations in RYR1 in malignant hyperthermia and central core disease. Hum Mutat 2006;27:977–89
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| MH susceptibility conferring in North America by which test? | Caffeine-Halothane Contracture Test | positive live muscle biopsy(CHCT)or in vitro contracture test (IVCT) in Europe |
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| A class of inherited skeletal muscle diseases characterized by impaired relaxation after sudden, voluntary muscle contraction | Myotonias | result from skeletal muscle membrane hyperexcitability, inappropriate firing, delay in muscle relaxation, and resultant contracture states of varying severity and duration |
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